Recurrence and visual outcomes of phototherapeutic keratectomy in lattice corneal dystrophy: a cohort study
Author
Sauvageot, Paola
Julio, Gemma
Bolaños, Jennifer V.
Carrera, Marta
de Toledo, Juan Álvarez
Barraquer, Rafael Ignacio
Publication date
2022ISSN
1081-597X
Abstract
PURPOSE:To evaluate recurrence and visual outcomes of phototherapeutic keratectomy (PTK) in lattice corneal dystrophy. METHODS:Kaplan-Meier survival analyses were retrospectively performed. Recurrence was defined as central biomicroscopic findings of recurrence with decreased visual acuity: loss of at least two lines or visual acuity ≤ 20/40) at any time during the follow-up. RESULTS:Twenty-two virgin eyes and 10 with previous keratoplasty (20 patients; 13 women and 7 men) were studied during a mean of 4.7 ± 3.5 years (range: 11 months to 18 years). One and 5 years after the first PTK (PTK1), 1 of 32 and 12 of 32 eyes, respectively, recurred. The cumulative probabilities of recurrence were 3%, 48%, and 89% in the whole sample at 1, 5, and 10 years, respectively. All cases in the virgin group and 8 eyes in the previous keratoplasty group improved their visual acuity. There were no significant differences in recurrence probability between groups (log-rank test; P = .86). A second PTK (PTK2) was performed in 15 of 32 eyes, with 6 postoperative recurrences recorded. The cumulative probabilities of recurrence in the whole sample were 18%, 30%, and 44% at 1, 3, and 5 years, respectively. Visual acuity improved in 11 of 13 eyes in the virgin group and 2 of 2 eyes in the previous keratoplasty group. Recurrence probability after PTK1 and PTK2 was similar in the whole sample (log-rank test; P = .637). Persistent graft edema after PTK1 in one eye was the only complication found. CONCLUSIONS:PTK can be an effective, safe, and repeatable treatment to delay keratoplasty in symptomatic lattice corneal dystrophy.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
617 - Surgery. Orthopaedics. Ophthalmology
Keywords
Oftalmologia
Oftalmología
Ophtalmology
Pages
6
Publisher
SLACK Journals
Collection
38;1
Is part of
Journal of Refractive Surgery
Citation
Sauvageot, Paola; Julio, Gemma; Bolaños, Jennifer V. [et al.]. Recurrence and visual outcomes of phototherapeutic keratectomy in lattice corneal dystrophy: a cohort study. Journal of Refractive Surgery, 2022, 38(1), p. 43-49. Disponible en: <https://journals.healio.com/doi/10.3928/1081597X-20211104-01>. Fecha de acceso: 5 feb. 2024. DOI: 10.3928/1081597X-20211104-01
This item appears in the following Collection(s)
- Ciències de la Salut [725]
Rights
2022, SLACK Incorporated