Recurrence and visual outcomes of phototherapeutic keratectomy in lattice corneal dystrophy: a cohort study
Autor/a
Sauvageot, Paola
Julio, Gemma
Bolaños, Jennifer V.
Carrera, Marta
de Toledo, Juan Álvarez
Barraquer, Rafael Ignacio
Data de publicació
2022ISSN
1081-597X
Resum
PURPOSE:To evaluate recurrence and visual outcomes of phototherapeutic keratectomy (PTK) in lattice corneal dystrophy. METHODS:Kaplan-Meier survival analyses were retrospectively performed. Recurrence was defined as central biomicroscopic findings of recurrence with decreased visual acuity: loss of at least two lines or visual acuity ≤ 20/40) at any time during the follow-up. RESULTS:Twenty-two virgin eyes and 10 with previous keratoplasty (20 patients; 13 women and 7 men) were studied during a mean of 4.7 ± 3.5 years (range: 11 months to 18 years). One and 5 years after the first PTK (PTK1), 1 of 32 and 12 of 32 eyes, respectively, recurred. The cumulative probabilities of recurrence were 3%, 48%, and 89% in the whole sample at 1, 5, and 10 years, respectively. All cases in the virgin group and 8 eyes in the previous keratoplasty group improved their visual acuity. There were no significant differences in recurrence probability between groups (log-rank test; P = .86). A second PTK (PTK2) was performed in 15 of 32 eyes, with 6 postoperative recurrences recorded. The cumulative probabilities of recurrence in the whole sample were 18%, 30%, and 44% at 1, 3, and 5 years, respectively. Visual acuity improved in 11 of 13 eyes in the virgin group and 2 of 2 eyes in the previous keratoplasty group. Recurrence probability after PTK1 and PTK2 was similar in the whole sample (log-rank test; P = .637). Persistent graft edema after PTK1 in one eye was the only complication found. CONCLUSIONS:PTK can be an effective, safe, and repeatable treatment to delay keratoplasty in symptomatic lattice corneal dystrophy.
Tipus de document
Article
Versió del document
Versió publicada
Llengua
Anglès
Matèries (CDU)
617 - Cirurgia. Ortopèdia. Oftalmologia
Paraules clau
Oftalmologia
Oftalmología
Ophtalmology
Pàgines
6
Publicat per
SLACK Journals
Col·lecció
38;1
Publicat a
Journal of Refractive Surgery
Citació
Sauvageot, Paola; Julio, Gemma; Bolaños, Jennifer V. [et al.]. Recurrence and visual outcomes of phototherapeutic keratectomy in lattice corneal dystrophy: a cohort study. Journal of Refractive Surgery, 2022, 38(1), p. 43-49. Disponible en: <https://journals.healio.com/doi/10.3928/1081597X-20211104-01>. Fecha de acceso: 5 feb. 2024. DOI: 10.3928/1081597X-20211104-01
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Drets
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