High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial
Author
Marco, Ester
Ramírez-Sarmiento, Alba L
Coloma, Ana
Sartor, Monique
Comin-Colet, Josep
Vila, Joan
Enjuanes, Cristina
Bruguera, Jordi
Escalada, Ferran
Gea, Joaquim
Orozco-Levi, Mauricio
Publication date
2014ISSN
1388-9842
Abstract
Aims: The purpose of this study was to evaluate the effectiveness, feasibility, and safety of a 4-week high-intensity inspiratory muscle training (hi-IMT) in patients with chronic heart failure (CHF). Methods and results: A double-blind randomized clinical trial was carried out in 22 patients with CHF. Participants were assigned to the hi-IMT or sham-IMT group. The trainer device was a prototype of the Orygen-Dual Valve®. The training workloads were adjusted weekly at the inspiratory pressure which allowed the performance of 10 consecutive maximal repetitions (10RM). Main outcomes were strength and endurance of the respiratory muscles assessed by maximal respiratory pressures (PImax and PEmax) and a 10RM manoeuvre, respectively. Twenty-one patients presented impairment in respiratory muscle strength and endurance. Patients in the hi-IMT group showed a significant improvement in both strength and endurance: inspiratory muscle strength in the intervention group increased 57.2% compared with 25.9% in the control group (P = 0.001). The percentage change in endurance was 72.7% for the hi-IMT group compared with 18.2% in the sham-IMT group (P < 0.001). No adverse effects occurred during the intervention. Conclusion: A 4-week hi-IMT with the use of the Orygen-Dual Valve® is shown to be an effective, feasible, and safe tool to improve weakness and fatigue of the inspiratory muscles. The key point of this study is to discuss immediate practical implications in terms of respiratory muscle dysfunction postulated as a potential prognostic factor and as an additional therapeutic target.
Document Type
Article
Language
English
Subject (CDU)
61 - Medical sciences
616.1 - Pathology of the circulatory system, blood vessels. Cardiovascular complaints
Keywords
Cardiologia
Cardiología
Cardiology
Pages
9
Publisher
Wiley
Collection
15; 8
Is part of
European Journal of Heart Failure
Citation
Marco, Ester; Ramírez-Sarmiento, Alba L; Coloma, Ana [et al.]. High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial. European Journal of Heart Failure, 15(8), p. 892-901. Disponible en: <https://onlinelibrary.wiley.com/doi/10.1093/eurjhf/hft035>. Fecha de acceso: 26 ene. 2024. DOI: 10.1093/eurjhf/hft035
This item appears in the following Collection(s)
- Ciències de la Salut [745]
Rights
© 2014 John Wiley & Sons