A perspective on the role of physiological stresses in cancer, diabetes and cognitive disease as environmental diseases
Autor/a
Esterhuizen, Maranda
Park, Chang-Beom
Kim, Young Jun
Kim, Tae-Young
Yoon, Hakwon
Andres, Frederic
Rodriguez Rodriguez, Rosalia
Tanabe, Shihori
Fecha de publicación
2023ISSN
2296-889X
Resumen
With rapid industrialization, urbanization, and climate change, the impact of environmental factors on human health is becoming increasingly evident and understanding the complex mechanisms involved is vital from a healthcare perspective. Nevertheless, the relationship between physiological stress resulting from environmental stressors and environmental disease is complex and not well understood. Chronic exposure to environmental stressors, such as air and water contaminants, pesticides, and toxic metals, has been recognized as a potent elicitor of physiological responses ranging from systemic inflammation to immune system dysregulation causing or progressing environmental diseases. Conversely, physiological stress can exacerbate susceptibility to environmental diseases. Stress-induced alterations in immune function and hormonal balance may impair the ability to detoxify harmful substances and combat pathogens. Additionally, prolonged stress can impact lifestyle choices, leading to harmful behaviors. Understanding the link between physiological stress and environmental disease requires a systematic, multidisciplinary approach. Addressing this complex relationship necessitates the establishment of a global research network. This perspective discusses the intricate interplay between physiological stress and environmental disease, focusing on common environmental diseases, cancer, diabetes, and cognitive degeneration. Furthermore, we highlight the intricate and reciprocal nature of the connection between physiological stress and these environmental diseases giving a perspective on the current state of knowledge as well as identifying where further information is necessary. Recognizing the role of physiological stress in environmental health outcomes will aid in the development of comprehensive strategies to safeguard public health and promote ecological balance.
Tipo de documento
Artículo
Versión del documento
Versión publicada
Lengua
English
Materias (CDU)
61 - Medicina
616 - Patología. Medicina clínica. Oncología
Palabras clave
Estressors ambientals
Espècies reactives de l'oxigen
Malalties ambientals
Salut humana
Càncer
Funció cognitiva
Diabetis
Factores estresantes ambientales
Especies reactivas de oxígeno
Enfermedades ambientales
Salud humana
Cáncer
Función cognitiva
Diabetes
Environmental stressors
Reactive oxygen species
Environmental disease
Human health
Cancer
Cognitive function
Diabetes
Páginas
7
Publicado por
Frontiers Media
Colección
10
Publicado en
Frontiers in Molecular Biosciences
Citación
Esterhuizen, Maranda; Park, Chang-Beom; Kim, Young Jun [et al.]. A perspective on the role of physiological stresses in cancer, diabetes and cognitive disease as environmental diseases. Frontiers in Molecular Biosciences, 10, 1274221. Disponible en: <https://www.frontiersin.org/articles/10.3389/fmolb.2023.1274221/full>. Fecha de acceso: 15 ene. 2024. DOI: 10.3389/fmolb.2023.1274221
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Derechos
© 2023 Esterhuizen, Park, Kim, Kim, Yoon, Andres, Rodriguez-Rodriguez and Tanabe. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.