Palladium nanoparticles synthesized by laser ablation in liquids for antimicrobial applications
Autor/a
Fernández Arias, Mónica
Vilas, Ana M.
Boutinguiza Larosi, Mohamed
Rodriguez, Daniel
Arias-González, Felipe
Pou Álvarez, Pablo
Riveiro Rodriguez, Antonio
Pou, Juan
Fecha de publicación
2022ISSN
2079-4991
Resumen
Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles’ size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells.
Tipo de documento
Artículo
Versión del documento
Versión publicada
Lengua
Inglés
Materias (CDU)
616.3 - Patología del aparato digestivo. Odontología
Palabras clave
Nanopartícules de pal·ladi
Ablació làser
Caracterització fisicoquímica
Bactericida activitat
Citocompatibilitat
Nanopartículas de paladio
Ablación laser
Caracterización fisicoquímica
Bactericida actividad
Citocompatibilidad
Palladium nanoparticles
Laser ablation
Physicochemical characterization
Bactericidal activity
Cytocompatibility
Páginas
18
Publicado por
MDPI
Publicado en
Nanomaterials
Citación
Fernández Arias, Mónica; Vilas, Ana M.; Boutinguiza Larosi, Mohamed [et al.]. Palladium nanoparticles synthesized by laser ablation in liquids for antimicrobial applications. Nanomaterials, 2022, 12(15), 2621. Disponible en: <https://www.mdpi.com/2079-4991/12/15/2621>. Fecha de acceso: 3 nov. 2022. DOI: 10.3390/nano12152621
Enlace al documento relacionado
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- Odontologia [228]
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