The use of ultrasonography to evaluate muscle thickness and subcutaneous fat in children and adolescents with cystic fibrosis
Author
Pereira de Souza, Rodrigo
Fagundes Donadio, Márcio Vinícius
Heinzmann‑Filho, João Paulo
Reimann Baptista, Rafael
Araújo Pinto, Leonardo
Epifanio, Matias
Cauduro Marostica, Paulo José
Publication date
2018ISSN
1984-0462
Abstract
Objective: To compare muscle thickness and subcutaneous fat in cystic fibrosis (CF) patients and healthy controls using ultrasonography (US), and to correlate US findings with nutritional, clinical and functional variables. Methods: Patients aged 6 to 18 years old with a diagnosis of CF and healthy controls were included. Participants underwent anthropometric measurements, an ultrasonographic evaluation of muscle thickness and subcutaneous fat in the triceps, quadriceps, and gastrocnemius regions, and skinfold thickness measurements. Body fat percentage was estimated using skinfold measurement. Subjects with CF also underwent a pulmonary function assessment using spirometry. Results: We studied 39 CF patients and 45 controls. A lower body mass index was observed in CF patients (p=0.011). Body composition and muscle thickness were similar between the groups. Only calf (p=0.023) circumference and femur diameter (p<0.001) were lower in CF patients. Although there were no significant between‑group differences in the comparison of US measurements of subcutaneous fat, CF patients exhibited decreased skinfold thickness in the triceps (p=0.031) and quadriceps (p=0.019). Moreover, there were weak and moderate correlations of US quadricep thickness with forced vital capacity (FVC) and lean mass, respectively. Moderate correlations of the triceps, quadriceps and gastrocnemius between US subcutaneous fat and skinfold measurements were found.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Ultrasonografia
Composició del cos
Plec de la pell gruix
Fibrosi quística
Pediatria
Ultrasonografía
Composición corporal
Pliegue cutáneo espesor
Fibrosis quística
Pediatría
Ultrasonography
Body composition
Skinfold thickness
Cystic fibrosis
Pediatrics
Pages
9
Publisher
Sociedade de Pediatria de São Paulo
Collection
36; 4
Is part of
Revista Paulista de Pediatria
Citation
Pereira de Souza, Rodrigo; Fagundes Donadio, Márcio Vinícius; Heinzmann‑Filho, João Paulo [et al.]. The use of ultrasonography to evaluate muscle thickness and subcutaneous fat in children and adolescents with cystic fibrosis. Revista Paulista de Pediatria, 2018, 36(49, p. 457-465. Disponible en: <https://www.scielo.br/j/rpp/a/kwWbLCYgnXbn5SzrhjMk3Ch/?format=pdf&lang=en>. Fecha de acceso: 28 mar. 2022. DOI: 10.1590/1984‑0462/;2018;36;4;00015
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/