Use of porous titanium trabecular as a bone defect regenerator: in vivo study
Autor/a
Torres Pérez, Ana Isabel
Fernandez-Fairen, Mariano
Torres Pérez, Ángel Antonio
Gil Mur, Francisco Javier
Data de publicació
2022ISSN
2075-4701
Resum
The application of porous materials is increasingly being used in orthopaedic surgery due to its good results. Bone growth within the pores results in excellent mechanical fixation with the bone, as well as good bone regeneration. The pores, in addition to being colonised by bone, produce a decrease in the modulus of elasticity that favours the transfer of loads to the bone. This research shows the results of an experimental study where we have created critical osteoperiosteal defects of 10 mm on rabbit’s radius diaphysis. In one group of 10 rabbits (experimental group) we have implanted a bioactive porous titanium cylinder, and in another group we have allowed spontaneous regeneration (control group). Mechanical tests were performed to assess the material. Image diagnostic techniques (X-ray, scanner and 3D scan: there are no references on the literature with the use of CT-scan in bone defects) and histological and histomorphometric studies post-op and after 3, 6 and 12 months after the surgery were performed. All the control cases went through a pseudoarthrosis. In 9 of the 10 cases of the experimental group complete regeneration was observed, with a normal cortical-marrow structure established at 6 months, similar to normal bone. Titanium trabecular reached a bone percentage of bone inside the implant of 49.3% on its surface 3 months post-op, 75.6% at 6 months and 81.3% at 12 months. This porous titanium biomaterial has appropriate characteristics to allow bone ingrowth, and it can be proposed as a bone graft substitute to regenerate bone defects, as a scaffold, or as a coating to achieve implant osteointegration.
Tipus de document
Article
Versió del document
Versió publicada
Llengua
Anglès
Matèries (CDU)
616.3 - Patologia de l'aparell digestiu. Odontologia
Paraules clau
Titani porós
Regeneració òssia
Osteointegració
Tomografia computaritzada
Titanio poroso
Regeneración ósea
Tomografía computarizada
Osteointegración
Porous titanium
Bone regeneration
CT-SCAN
Osseointegration
Pàgines
13
Publicat per
MDPI
Col·lecció
12;2
Publicat a
Metals
Citació
Torres Pérez, Ana Isabel; Fernández Fairén, Mariano; Torres Pérez, Ángel Antonio [et al.]. Use of porous titanium trabecular as a bone defect regenerator: in vivo study. Metals, 2022, 12(2), 327. Disponible en: <https://www.mdpi.com/2075-4701/12/2/327>. Fecha de acceso: 22 feb. 2022. DOI: 10.3390/met12020327
Número de l'acord de la subvenció
info:eu-repo/grantAgreement/MICINN/RTI2018-098075-B-C22
Aquest element apareix en la col·lecció o col·leccions següent(s)
- Odontologia [228]
Drets
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