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Now showing items 11-18 of 18
Application of percutaneous needle electrolysis does not elicit temperature changes: an in vitro cadaveric study
(MDPI, 2022)
Percutaneous needle electrolysis (PNE) consists of the ultrasound-guided application of a galvanic electrical current through a solid filament needle. One proposed therapeutic mechanism for this ...
Assessing the potential role of copper and cobalt in stimulating angiogenesis for tissue regeneration
(Public Library of Science, 2021)
The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations ...
Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice
(Springer Nature, 2021)
Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in ...
Engineering a genome reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
(EMBO Press, 2021)
Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated ...
Skull fractures by glass bottles tested on cadaveric heads
(Springer Nature, 2023)
Head trauma is frequently related to the misuse of drinking vessels as weapons. Forensic reports usually evaluate these blunt injuries as having occurred in scenarios where the alcohol intake is high. ...
Improving signal/noise resolution in single-molecule experiments using molecular constructs with short handles
(Elsevier, 2011)
We investigate unfolding/folding force kinetics in DNA hairpins exhibiting two and three states with newly designed short dsDNA handles (29 bp) using optical tweezers. We show how the higher stiffness ...
Single-molecule stochastic resonance
(American Physical Society, 2012)
Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ...
A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
(Springer Nature, 2024)
In hormone-responsive breast cancer cells, progesterone (P4) has been shown to act via its nuclear receptor (nPR), a ligand-activated transcription factor. A small fraction of progesterone receptor is ...