Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome
Author
Dietl, Beatriz
Henares, Desirée
Boix-Palop, Lucía
Garau, Javier
Calbo Sebastián, Esther
Publication date
2021-04ISSN
2296-858X
Abstract
Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main aetiological agent of community-acquired pneumonia (CAP). In the last decades, several factors related to the host, the microorganism and the antibiotic therapy have been investigated to identify risk factors associated with the development of invasive pneumococcal disease (IPD). Nevertheless, these factors themselves do not explain the risk of developing disease or its severity. Recently, some studies have focused on the importance of nasopharyngeal (NP) microbiome and its relation to respiratory health. This review presents existing evidence of the potential role of NP microbiome in the development of IPD.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
616.2 - Pathology of the respiratory system. Complaints of the respiratory organs
Keywords
Microbiologia
Rinofaringe
Infecció
Aparell respiratori -- Malalties
Pneumònia
Pneumococs
Microorganismes
Antibiòtics
Microbiología
Nasofaringe
Infecciones
Aparato respiratorio -- Enfermedades
Neumonía
Streptococcus pneumoniae
Microorganismos
Antibióticos
Microbiology
Rhinopharynx
Infection
Respiratory system -- Diseases
Pneumonia
Pneumococcus
Microorganisms
Antibiotics
Pages
10
Publisher
Frontiers Media
Collection
8;
Is part of
Frontiers in Medicine
Citation
Dietl, Beatriz; Henares, Desirée; Boix-Palop, Lucía [et al.]. Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome. Frontiers in Medicine, 2021, 8, 650271. Disponible en: <https://www.frontiersin.org/articles/10.3389/fmed.2021.650271/full>. Fecha de acceso: 28 may. 2021. DOI: 10.3389/fmed.2021.650271
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
© 2021 Dietl, Henares, Boix-Palop, Muñoz-Almagro, Garau and Calbo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/