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Pneumonia in children admitted to the national referral hospital in Bhutan: a prospective cohort study
dc.contributor.author | Jullien, Sophie | |
dc.contributor.author | Pradhan, Dinesh | |
dc.contributor.author | Tshering, Tashi | |
dc.contributor.author | Sharma, Ragunath | |
dc.contributor.author | Dema, Kumbu | |
dc.contributor.author | Garcia-Garcia, Selene | |
dc.contributor.author | Ribó, Jose Luis | |
dc.contributor.author | Muñoz-Almagro, Carmen | |
dc.contributor.author | Bassat, Quique | |
dc.date.accessioned | 2021-02-16T14:58:48Z | |
dc.date.available | 2021-02-16T14:58:48Z | |
dc.date.issued | 2020-06 | |
dc.identifier.citation | Jullien, Sophie; Pradhan, Dinesh; Tshering, Tashi [et al.]. Pneumonia in children admitted to the national referral hospital in Bhutan: a prospective cohort study. International Journal of Infectious Diseases, 2020, 95, p. 74-83. Disponible en: <https://www.sciencedirect.com/science/article/pii/S1201971220302332?via%3Dihub>. Fecha de acceso: 16 feb. 2021. DOI: 10.1016/j.ijid.2020.04.017 | ca |
dc.identifier.issn | 1201-9712 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/1996 | |
dc.description.abstract | Objectives: The study aim was to describe the etiological profile and clinical characteristics of pneumonia among children hospitalized in Thimphu, Bhutan. Methods: This prospective study enrolled children aged 2–59 months admitted to the Jigme Dorji Wangchuck National Referral Hospital with World Health Organization (WHO)-defined clinical pneumonia. Demographic and clinico-radiological data were collected through questionnaires, physical examination, and chest radiography. Blood samples and nasopharyngeal washing were collected for microbiological analysis including culture and molecular methods. Results: From July 2017 to June 2018, 189 children were enrolled, of which 53.4% were infants. Pneumonia-related admissions were less frequent over the winter. Chest radiographies were obtained in 149 children; endpoints included pneumonia in 39 cases (26.2%), other infiltrates in 31 (20.8%), and were normal in 79 children (53.0%). Non-contaminated bacterial growth was detected in 8/152 (5.3%) blood cultures, with only two cases of Streptococcus pneumoniae. Viral detection in upper respiratory secretions was common, with at least one virus detected in 103/115 (89.6%). The three most-commonly isolated viruses were respiratory syncytial virus (52/115; 45.2%), rhinovirus (42/115; 36.5%), and human parainfluenza virus (19/115; 16.5%). A third of patients with viral infections showed mixed infections. Case fatality rate was 3.2% (6/189). Conclusion: Respiratory viral infections predominated among this cohort of WHO-defined clinical pneumonia cases, whereas bacterial aetiologies were uncommon, highlighting the epidemiologic transition that Bhutan seems to have reached. | ca |
dc.format.extent | 10 | ca |
dc.language.iso | eng | ca |
dc.publisher | Elsevier | ca |
dc.relation.ispartof | International Journal of Infectious Diseases | ca |
dc.relation.ispartofseries | 95; | |
dc.rights | © 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). International Journal of Infectious Diseases 95 (2020 ) 74–83 Contents lists available at Science Direct International Journal of Infectious Diseases journal homepage: www.elsevier.com/locate/ijid | ca |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.other | Pneumònia | ca |
dc.subject.other | Infecció | ca |
dc.subject.other | Virus | ca |
dc.subject.other | Epidemiologia | ca |
dc.subject.other | Infants -- Salud i higiene | ca |
dc.subject.other | Neumonía | es |
dc.subject.other | Infección | es |
dc.subject.other | Virus | es |
dc.subject.other | Epidemiología | es |
dc.subject.other | Niños -- Salud e higiene | es |
dc.subject.other | Pneumonia | en |
dc.subject.other | Infection | en |
dc.subject.other | Virus | en |
dc.subject.other | Epidemiology | en |
dc.subject.other | Children -- Health and hygiene | en |
dc.title | Pneumonia in children admitted to the national referral hospital in Bhutan: a prospective cohort study | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.subject.udc | 61 | ca |
dc.identifier.doi | https://dx.doi.org/10.1016/j.ijid.2020.04.017 | ca |
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