Ciències de la Salut: Enviaments recents
Ara mostrant els elements 1-20 de 734
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Novel nanostructured lipid carriers loading Apigenin for anterior segment ocular pathologies
(International Journal of Pharmaceutics, 2024)Dry eye disease (DED) is a chronic multifactorial disorder of the ocular surface caused by tear film dysfunction and constitutes one of the most common ocular conditions worldwide. However, its treatment ... -
Foetal haemoglobin as a marker of bone marrow suppression secondary to anti-kell alloimmunisation
(International Journal of Neonatal Screening, 2023)Anti-Kell alloimmunisation is a potentially severe minor blood group type incompatibility, not only as a cause of haemolytic disease of the foetus and newborn, but also due to the destruction of red ... -
The wish to hasten death in patients with life-limiting conditions. A systematic overview
(Journal of Pain and Symptom Management, 2024)Context: A systematic review of the wish to hasten death among people with life-limiting conditions was published in 2011. Since then, other reviews and primary studies have been published that have ... -
Establishing standardization guidelines for finite-element optomechanical simulations of refractive laser surgeries: an application to photorefractive keratectomy
(Translational Vision Science & Technology, 2024)Purpose: Computational models can help clinicians plan surgeries by accounting for factors such as mechanical imbalances or testing different surgical techniques beforehand. Different levels of modeling ... -
The use of simulation in nursing education programs: a cross-sectional interuniversity study
(Nursing Forum, 2024)Background. Simulation-based education has been incorporated into nursing curricula as an educational strategy. However, its implementation has not yet been standardized in different regions. Purpose. ... -
Efficacy of aerobic exercise on widespread pain sensitization in patients with temporomandibular disorders: a preliminary randomized controlled study
(Applied Economics, 2024)Myogenic temporomandibular disorders (TMDs) are commonly associated with pain sensitization (PS), manifesting decreased local and distal pressure pain thresholds (PPTs). Aerobic exercise (AE) has shown ... -
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
(Molecular Oncology, 2023)Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ... -
Lung ultrasound and procalcitonin, improving antibiotic management and avoiding radiation exposure in pediatric critical patients with bacterial pneumonia: a randomized clinical trial
(European Journal of Medical Research, 2024)Background: Pneumonia is a major public health problem with an impact on morbidity and mortality. Its management still represents a challenge. The aim was to determine whether a new diagnostic algorithm ... -
Consumo de tabaco en Costa Rica: ¿está el país preparado para el “fin del juego”?
(Revista Panamericana de Salud Pública, 2024)El consumo de tabaco es, todavía, uno de los principales factores de riesgo de morbilidad y mortalidad en todo el mundo. Sin embargo, las acciones realizadas para el control del tabaco en las últimas ... -
Cervical manipulation versus thoracic or cervicothoracic manipulations for the management of neck pain. A systematic review and meta-analysis
(Musculoskeletal Science and Practice, 2024)Background: Cervical and thoracic thrust or non-thrust manipulations have shown to be effective in patients with neck pain, but there is a lack of studies comparing both interventions in patients with ... -
K-means clustering identifies diverse clinical phenotypes in COVID-19 patients: implications for mortality risks and remdesivir impact
(12, 2024)Introduction: The impact of remdesivir on mortality in patients with COVID-19 is still controversial. We aimed to identify clinical phenotype clusters of COVID-19 hospitalized patients with highest ... -
Oozing: an accessible technique to create 3D-printed scaffolds suitable for tissue engineering
(International Journal of Bioprinting, 2024)Tissue-engineered constructs require mimicking the extracellular matrix microenvironment of native tissue for better promoting cell growth. Commercial three-dimensional (3D) printers provide a versatile ... -
Effect of functionalization of texturized polypropylene surface by silanization and HBII-RGD attachment on response of primary abdominal and vaginal fibroblasts
(Polymers, 2024)Soft tissue defects, such as incisional hernia or pelvic organ prolapse, are prevalent pathologies characterized by a tissue microenvironment rich in fragile and dysfunctional fibroblasts. Precision ... -
The use of simulation in nursing education programs: a cross-sectional interuniversity study
(Hindawi, 2024)Background. Simulation-based education has been incorporated into nursing curricula as an educational strategy. However, its implementation has not yet been standardized in different regions. Purpose. ... -
How do sports injury epidemiological outcomes vary depending on athletes' response rates to a weekly online questionnaire? An analysis of 39-week follow-up from 391 athletics (track and field) athletes
(Scandinavian Journal of Medicine & Science in Sports, 2024)Objective: To explore how sports injury epidemiological outcomes (i.e., prevalence, average prevalence, incidence, burden, and time to first injury) vary depending on the response rates to a weekly ... -
Cell-cycle inhibition and immune microenvironment in breast cancer treated with ribociclib and letrozole or chemotherapy
(npj Breast Cancer, 2024)In this study, we performed genomic analyses of cell cycle and tumor microenvironment changes during and after ribociclib and letrozole or chemotherapy in the CORALLEEN trial. 106 women with untreated ... -
The effects of soft-tissue techniques and exercise in the treatment of patellar tendinopathy—systematic review and meta-analysis
(Healthcare, 2024)Background: Patellar tendinopathy is a degenerative clinical disorder that causes load-related pain in the lower pole of the patella or patellar tendon. It predominantly affects young male athletes ... -
Effect of a home-base core stability exercises in hereditary ataxia. A randomized controlled trial. A pilot randomized controlled trial
(Movement Disorders Clinical Practice, 2024)Background: Core stability exercises (CSE) have been shown to be effective in improving trunk function in several neurological diseases, but the evidence is scarce on Hereditary Ataxias (HA). Objective: ... -
The thrombotic risk in Cushing’s syndrome—questions, answers, and the algorithm to consider in its assessment: part I—thrombotic risk not related to surgery
(Frontiers in Endocrinology, 2024)Introduction: Recently, it has been reported that there is a great diversity in strategies used for thromboprophylaxis in patients with Cushing’s syndrome (CS). An aim of this review was to discuss these ... -
Effectiveness of one and two doses of acellular pertussis vaccines against laboratory-confirmed pertussis requiring hospitalisation in infants: Results of the PERTINENT sentinel surveillance system in six EU/EEA countries, December 2015 – December 2019
(Vaccine, 2024)Background: Monitoring effectiveness of pertussis vaccines is necessary to adapt vaccination strategies. PERTINENT, Pertussis in Infants European Network, is an active sentinel surveillance system ...