Browsing Odontologia by Author "Fischer, Nicholas G."
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Biomimetic mineralized hybrid scaffolds with antimicrobial peptides
Ye, Zhou; Zhu, Xiao; Mutreja, Isha; Kumar Boda, Sunil; Fischer, Nicholas G.; Zhang, Anqi; Lui, Christine; Qi, Yipin; Aparicio, Conrado (Bioactive Materials, 2021-08)Infection in hard tissue regeneration is a clinically-relevant challenge. Development of scaffolds with dual function for promoting bone/dental tissue growth and preventing bacterial infections is a ... -
Culture and characterization of various porcine integumentary-connective tissue-derived mesenchymal stromal cells to facilitate tissue adhesion to percutaneous metal implants
Dey, Devaveena; Fischer, Nicholas G.; Dragon, Andrea H.; Ronzier, Elsa; Mutreja, Isha; Danielson, David T.; Homer, Cole J.; Forsberg, Jonathan A.; Bechtold, Joan E.; Aparicio, Conrado; Davis, Thomas A. (Stem Cell Research & Therapy, 2021)Background: Transdermal osseointegrated prosthesis have relatively high infection rates leading to implant revision or failure. A principle cause for this complication is the absence of a durable ... -
Implant surface physicochemistry affects keratinocyte hemidesmosome formation
Raptopoulos, Michail; Fischer, Nicholas G.; Aparicio, Conrado (Journal of Biomedical Materials Research Part A, 2023)Previous studies have shown hydrophilic/hydrophobic implant surfaces stimulate/hinder osseointegration. An analogous concept was applied here using common biological functional groups on a model surface ... -
Junctional epithelium and hemidesmosomes: tape and rivets for solving the “percutaneous device dilemma” in dental and other permanent implants
Fischer, Nicholas G.; Aparicio, Conrado (Bioactive Materials, 2022-12)The percutaneous device dilemma describes etiological factors, centered around the disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant percutaneous device infection. ...