Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering
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Autor/a
Rodríguez González, Raquel
Otros/as autores/as
Pérez Antoñanzas, Román
Delgado Garoña, Luis María
Universitat Internacional de Catalunya. Departament de Ciències Bàsiques
Fecha de defensa
2023-05-31T17:41:13Z2023-02-07
2025-02-06T01:00:00Z
Resumen
The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large bone defects by itself. Nowadays, grafting is the main therapy, which is the replacement of missing bone with a graft. However, the use of grafts has some drawbacks, such as a limited availability, tissue rejection, donor site morbidity and infection. For this reason, Tissue Engineering has focused on the development of synthetic grafts in the form of scaffolds which are three dimensional porous structures that provide a 3D environment for the adhesion, proliferation, and differentiation of cells to produce new bone.
Tipo de documento
Tesis
Versión publicada
Lengua
Inglés
Materias y palabras clave
Silica
Hybrids
Hybrids
3D Printing
Bone regeneration
Sol-gel
Inks
Silica-gelatin
Tissue engineering
Gelatin
Ciencias de la salud
61
Páginas
199 p.
application/pdf
Publicado por
Universitat Internacional de Catalunya
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http://creativecommons.org/licenses/by-nc-nd/4.0/