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dc.contributor.authorGarcía de Oteyza, Gonzalo
dc.contributor.authorÁlvarez de Toledo, Juan
dc.contributor.authorBarraquer, Rafael I.
dc.contributor.authorKling, Sabine
dc.date.accessioned2024-02-14T15:39:07Z
dc.date.available2024-02-14T15:39:07Z
dc.date.issued2023
dc.identifier.citationGarcía de Oteyza, Gonzalo; Álvarez de Toledo, Juan; Barraquer, Rafael I. [et al.]. Localized refractive changes induced by symmetric and progressive asymmetric intracorneal ring segments assessed with a 3D finite-element model. Bioengineering, 2023, 10(9), 1014. Disponible en: <https://www.mdpi.com/2306-5354/10/9/1014>. Fecha de acceso: 14 feb. 2024. DOI: 10.3390/bioengineering10091014ca
dc.identifier.issn2306-5354ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/4093
dc.description.abstractTo build a representative 3D finite element model (FEM) for intracorneal ring segment (ICRS) implantation and to investigate localized optical changes induced by different ICRS geometries, a hyperelastic shell FEM was developed to compare the effect of symmetric and progressive asymmetric ICRS designs in a generic healthy and asymmetric keratoconic (KC) cornea. The resulting deformed geometry was assessed in terms of average curvature via a biconic fit, sagittal curvature (K), and optical aberrations via Zernike polynomials. The sagittal curvature map showed a locally restricted flattening interior to the ring (Kmax −11 to −25 dpt) and, in the KC cornea, an additional local steepening on the opposite half of the cornea (Kmax up to +1.9 dpt). Considering the optical aberrations present in the model of the KC cornea, the progressive ICRS corrected vertical coma (−3.42 vs. −3.13 µm); horizontal coma (−0.67 vs. 0.36 µm); and defocus (2.90 vs. 2.75 µm), oblique trefoil (−0.54 vs. −0.08 µm), and oblique secondary astigmatism (0.48 vs. −0.09 µm) aberrations stronger than the symmetric ICRS. Customized ICRS designs inspired by the underlying KC phenotype have the potential to achieve more tailored refractive corrections, particularly in asymmetric keratoconus patterns.ca
dc.format.extent12ca
dc.language.isoengca
dc.publisherMDPIca
dc.relation.ispartofBioengineeringca
dc.relation.ispartofseries10;9
dc.rights© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).ca
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.otherModel d'elements finitsca
dc.subject.otherQueratoconca
dc.subject.otherCirurgia refractivaca
dc.subject.otherBiomecànica cornealca
dc.subject.otherElastografiaca
dc.subject.otherModel 3Dca
dc.subject.otherModelo de elementos finitosca
dc.subject.otherQueratoconoca
dc.subject.otherCirugía refractivaca
dc.subject.otherBiomecánica cornealca
dc.subject.otherElastografíaca
dc.subject.otherModelo 3Dca
dc.subject.otherFinite element modelca
dc.subject.otherKeratoconusca
dc.subject.otherRefractive surgeryca
dc.subject.otherCorneal biomechanicsca
dc.subject.otherElastographyca
dc.subject.other3D modelca
dc.titleLocalized refractive changes induced by symmetric and progressive asymmetric intracorneal ring segments assessed with a 3D finite-element modelca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc617ca
dc.identifier.doihttps://dx.doi.org/10.3390/bioengineering10091014ca


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© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/
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