Bacteriostatic poly rthylene glycol plasma coatings for orthodontic titanium mini-implants
Author
Barrera Mora, Jose Maria
Brizuela, Aritza
Espinar, Eduardo
Publication date
2022ISSN
1996-1944
Abstract
Titanium mini-implants are used as anchorage for orthodontic tooth movements. However, these implants present problems due to the infection of surrounding tissues. The aim of this work was to obtain a polyethylene glycol (PEG) layer by plasma in order to achieve a bacteriostatic surface. Titanium surfaces were activated by argon plasma and, after, by PEG plasma with different powers (100, 150 and 200 W) for 30 and 60 min. The roughness was determined by white light interferometer microscopy and the wettability was determined by the contact angle technique. Surface chemical compositions were characterized by X-ray photoelectron spectroscopy (XPS) and cytocompatibility and cell adhesion studies were performed with fibroblast (hFFs) and osteoblast (SAOS-2) cells. Bacterial cultures with Spectrococcus Sanguinis and Lactobacillus Salivarius were performed, and bacterial colonization was determined. The results showed that plasma treatments do not affect the roughness. Plasma makes the surfaces more hydrophilic by decreasing the contact angles from 64.2° for titanium to 5.2° for argon-activated titanium, with values ranging from 12° to 25° for the different PEG treatments. The plasma has two effects: the cleaning of the surface and the formation of the PEG layer. The biocompatibility results were, for all cases, higher than 80%. The polymerization treatment with PEG reduced the adhesion of hFFs from 7000 to 6000 and, for SAOS-2, from 14,000 to 6500, for pure titanium and those treated with PEG, respectively. Bacterial adhesion was also reduced from 600 to 300 CFU/mm2 for Spetrococcuns Sanguinis and from 10,000 to 900 CFU/mm2 for Lactobacillus Salivarius. The best bacteriostatic treatment corresponded to PEG at 100 W and 30 s. As a consequence, the PEG coating would significantly prevent the formation of bacterial biofilm on the surface of titanium mini-implants.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
616.3 - Pathology of the digestive system. Complaints of the alimentary canal
Keywords
Comportament bacteriostàtic
Mini-implants
Polietilenglicol
Titani
Ortodòncia
Comportamiento bacteriostático
Mini-implantes
Polietilenglicol
Titanio
Ortodoncia
Bacteriostatic behavior
Mini-implants
Poly ethylene glycol
Titanium
Orthodontics
Pages
13
Publisher
MDPI
Collection
15; 21
Is part of
Materials
Citation
Rodríguez Fernández, Juan Carlos; Pastor, Francisco; Barrera Mora, Jose Maria [et al.]. Bacteriostatic poly rthylene glycol plasma coatings for orthodontic titanium mini-implants. Materials, 2022, 15, 7487. Disponible en: <https://www.mdpi.com/1996-1944/15/21/7487>. Fecha de acceso: 29 nov. 2022. DOI: 10.3390/ma15217487
Link to the related item
This item appears in the following Collection(s)
- Odontologia [245]
Rights
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/