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dc.contributor.authorMarch-López, Pablo
dc.contributor.authorMadridejos, Rosa
dc.contributor.authorTomas, Rosa
dc.contributor.authorBoix-Palop, Lucía
dc.contributor.authorArcenillas, Paula
dc.contributor.authorGómez, Lucía
dc.contributor.authorPadilla, Emma
dc.contributor.authorXercavins, Mariona
dc.contributor.authorMartinez, Laura
dc.contributor.authorRiera, Montserrat
dc.contributor.authorBadia, Cristina
dc.contributor.authorNicolás, Jordi
dc.contributor.authorCalbo Sebastián, Esther
dc.date.accessioned2021-05-13T14:31:29Z
dc.date.available2021-05-13T14:31:29Z
dc.date.issued2020-04-02
dc.identifier.citationMarch-López, Pablo; Madridejos, Rosa; Tomas, Rosa [et al.]. Impact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental study. Frontiers in Pharmacology, 2020, 11, 398. Disponible en: <https://www.frontiersin.org/articles/10.3389/fphar.2020.00398/full>. Fecha de acceso: 13 may. 2021. DOI: 10.3389/fphar.2020.00398ca
dc.identifier.issn1663-9812ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/2536
dc.description.abstractThe aim of the study was to evaluate the impact of a multifaceted antimicrobial stewardship intervention on antibiotic consumption in a primary health care (PHC) area in Spain. Quasi-experimental study conducted in a PHC area with nine PHC centers, a 400-bed acute care teaching hospital, and 18 nursing homes serving a population of 260,561. The intervention was based on the 2016 CDC Core Elements of Outpatient Antibiotic Stewardship publication and targeted 130 PHC physicians, 41 PHC pediatricians, 19 emergency physicians, and 18 nursing home physicians. The components were commitment, actions for improving antibiotic prescribing, tracking and feedback, and education and experience. The primary outcome was overall antibiotic consumption. Secondary outcomes were consumption of antibiotics to treat pharyngotonsillitis, acute otitis media, acute sinusitis, acute bronchitis, and urinary tract infection (UTI), percentage of patients treated with specific antibiotics, and dispensing costs. Consumption was measured in defined daily doses per 1,000 inhabitants per day (DID) and compared pre- and postintervention (2016 vs. 2018). Overall antibiotic consumption decreased from 16.01 to 13.31 DID (−16.85%). Consumption of amoxicillin/clavulanic acid and quinolones decreased from 6.04 to 4.72 DID (−21.88%) and 1.64 to 1.23 DID (−25.06%), respectively. The percentage of patients treated with antibiotics decreased from 26.99 to 22.41%. The intervention resulted in cost savings of €72,673. Use of antibiotics to treat pharyngotonsillitis, UTI, and acute otitis media, sinusitis, and bronchitis decreased significantly. Our antimicrobial stewardship program led to a decrease in antibiotic consumption and significantly improved the use of antibiotics for the most prevalent PHC infections.en
dc.format.extent7ca
dc.language.isoengca
dc.publisherFrontiers Mediaca
dc.relation.ispartofFrontiers in Pharmacologyca
dc.relation.ispartofseries11;
dc.rights© 2020 March-López, Madridejos, Tomas, Boix, Arcenillas, Gómez, Padilla, Xercavins, Martinez, Riera, Badia, Nicolás and Calbo. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.otherAntibiòticsca
dc.subject.otherAtenció primàriaca
dc.subject.otherAntibióticoses
dc.subject.otherAtención primariaes
dc.subject.otherAntibioticsen
dc.subject.otherPrimary careen
dc.titleImpact of a multifaceted antimicrobial stewardship intervention in a primary health care area: a quasi-experimental studyen
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc61ca
dc.identifier.doihttps://dx.doi.org/10.3389/fphar.2020.00398ca


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© 2020 March-López, Madridejos, Tomas, Boix, Arcenillas, Gómez, Padilla, Xercavins, Martinez, Riera, Badia, Nicolás and Calbo. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with
these terms.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/