Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif

Molinos-Albert, Luis M.; Bilbao, Eneritz; Agulló, Luis [et al.]. Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif. Scientific Reports, vol. 7, e40800. Disponible en: <https://www.nature.com/articles/srep40800#Ack1>. Fecha de acceso: 7 mar. 2020. DOI: 10.1038/srep40800

Grant agreement number

info:eu-repo/grantAgreement/ES/3PN/BFU2012-33103

info:eu-repo/grantAgreement/ES/1PE/SAF2013-49042-R

Note

We are grateful to Jorge Díaz, Vanessa García and Ismael Varela from the Animal Facility of IGTP for excellent technical assistance. This work was supported by the HIVACAT Program, the CERCA Program (Generalitat de Catalunya), the Spanish AIDS network ‘Red Temática Cooperativa de Investigación en SIDA’ (RD12/0017/0002), the Fondo de Investigaciones Sanitarias and FEDER “Fondo Europeo de Desarrollo Regional” (grant number PI14/01307, to JB), the Basque Country Government (grant number IT838-13 to ML) and the Spanish Ministry of Economy (BFU2012-33103 to ML and FXC; and SAF2013-49042-R to JMP and NIU). The utilization of supercomputational facilities was supported by The Spanish Supercomputing Network (grant numbers BCV2015-2-0009 and BCV-2016-2-0005). J.B. is a researcher from Fundació Institut de Recerca en Ciències de la Salut Germans Trias i Pujol supported by the Health Department of the Catalan Government (Generalitat de Catalunya). LMM-A was supported by an FI predoctoral grant from Agència de Gestió d’Ajuts Universitaris i de Recerca from Generalitat de Catalunya and European Social Fund. JAN is supported by an FI predoctoral fellowship from the Basque Government. CV receives support from ISCIII-Subdirección General de Evaluación and Fondo-EU de Desarrollo Regional (FEDER) contract CP13/00174. CV and PJC are members of the CRP-TB (Group 17) of the Spanish Network CIBER Enfermedades Respiratorias. The following reagents were obtained through the NIH AIDS Reagent Program, Division of AIDS, NIAID, NIH: Anti-HIV-1 gp41 Monoclonal (D50) (Cat# 11393); HIV-1 Consensus Subtype B Env Peptide Set (cat# 9480).

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