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Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice
(American Society for Biochemistry and Molecular Biology, 2019-07)
The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain ...
Current challenges for targeting brown fat thermogenesis to combat obesity
(Frontiers Media S.A., 2020-10-27)
Just over a decade has passed since metabolically active brown adipose tissue (BAT) was unequivocally identified in healthy adult humans. Since then, researchers have provided evidence of expression of ...
CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
(Elsevier, 2019-01)
Objective: Carnitine palmitoyltransferase 1C (CPT1C) is implicated in central regulation of energy homeostasis. Our aim was to investigate whether CPT1C in the ventromedial nucleus of the hypothalamus ...
Editorial: current challenges for targeting brown fat thermogenesis to combat obesity
(Frontiers Media, 2020-10-27)
Just over a decade has passed since metabolically active brown adipose tissue (BAT) was unequivocally identified in healthy adult humans. Since then, researchers have provided evidence of expression of ...
Pomace olive oil concentrated in triterpenic acids restores vascular function, glucose tolerance and obesity progression in mice
(MDPI, 2020-01)
Pomace olive oil, an olive oil sub-product, is a promising source of bioactive triterpenoids such as oleanolic acid and maslinic acid. Considering the vascular actions of pomace olive oil and the potential ...