Search
Now showing items 301-310 of 614
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Elsevier, 2019-12)
Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ...
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
(American Society for Biochemistry and Molecular Biology, 2012)
A novel lyase activity enzyme is characterized for the first time: HMG-CoA lyase-like1 (er-cHL), which is a close homolog of mitochondrial HMG-CoA lyase (mHL). Initial data show that there are nine ...
Understanding patients’ experiences of the wish to hasten death: an updated and expanded systematic review and meta-ethnography
(BMJ Publishing Group, 2017)
Objectives: Patients with advanced disease sometimes express a wish to hasten death (WTHD). In 2012, we published a systematic review and meta-ethnography of qualitative studies examining the experience ...
Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
(American Society for Biochemistry and Molecular Biology, 2003-03-14)
Carnitine palmitoyltransferase (CPT) I, which catalyzes the conversion of palmitoyl-CoA to palmitoylcarnitine facilitating its transport through the mitochondrial membranes, is inhibited by malonyl-CoA. ...
The return of malonyl-CoA to the brain: cognition and other stories
(Elsevier, 2021-01)
Nutrients, hormones and the energy sensor AMP-activated protein kinase (AMPK) tightly regulate the intracel-lular levels of the metabolic intermediary malonyl-CoA, which is a precursor of fatty ...
Low resilience was a risk factor of mental health problems during the COVID-19 pandemic but not in individuals exposed to COVID-19: a cohort study in spanish adult general population
(MDPI, 2022)
Background: The aim is to analyze whether people with low resilience are at higher risk of mental health problems during the COVID-19 pandemic in Spanish adults. Methods: a longitudinal cohort study was ...
Isolated acute hemorrhagic edema of the eyelids
(ACT Publishing Group Limited, 2019-12)
Perivascular epithelioid cell tumors (PEComas) are rare tumors which can arise in almost every body site. Little is still known about these tumors because of the limited number of cases described by far ...
Hormone-control regions mediate steroid receptor–dependent genome organization
(Cold Spring Harbor Laboratory Press, 2019)
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...
Long-term efficacy and effectiveness of abehavioural and community-basedexercise intervention (Urban Training) toincrease physical activity in patients withCOPD: a randomised controlled trial
(European Respiratory Society, 2018)
There is a need to increase and maintain physical activity in patients with chronic obstructive pulmonary disease (COPD). We assessed 12-month efficacy and effectiveness of the Urban Training intervention ...
Determinants of study completion and response to a 12-month behavioral physical activity intervention in chronic obstructive pulmonary disease: a cohort study
(Public Library of Science, 2019-05-20)
Objectives: Physical activity is key to improve the prognosis of chronic obstructive pulmonary disease (COPD). To help to tailor future interventions we aimed to identify the baseline characteristics ...