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Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort
(Elsevier, 2017-06)
Background: The leading high-risk state for diabetes mellitus (DM) – prediabetes – is increasing; however, a lack of information exists in oldest old subjects. The objective of this study is to describe ...
Role of the NUDT enzymes in breast cancer
(MDPI, 2021)
Despite global research efforts, breast cancer remains the leading cause of cancer death in women worldwide. The majority of these deaths are due to metastasis occurring years after the initial treatment ...
Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning
(Optical Society of America, 2019-02-01)
Glaucoma detection in color fundus images is a challenging task that requires expertise and years of practice. In this study we exploited the application of different Convolutional Neural Networks (CNN) ...
Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): surveillance data from 23 sites in Catalonia, Spain
(Public Library of Science, 2020-02)
Background: The objective of this study is to describe incidence and shifts of serotype and clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups (<5 years, 5–17 ...
Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius
(Wiley, 2014-05-30)
Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ...
Limited joint mobility progression in type 1 diabetes: a 15-year follow-up study
(Hindawi Limited, 2018)
Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different ...
SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
(Springer Nature, 2020-09-10)
Background: Deficiency of mitochondrial sirtuin 3 (SIRT3), a NAD+-dependent protein deacetylase that maintains redox status and lipid homeostasis, contributes to hepatic steatosis. In this study, we ...
Biofabrication of collagen tissue-engineered blood vessels with direct co-axial extrusion
(MDPI, 2022)
Cardiovascular diseases are considered one of the worldwide causes of death, with atherosclerosis being the most predominant. Nowadays, the gold standard treatment is blood vessel replacement by bypass ...
Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle
(American Society for Biochemistry and Molecular Biology, 1994-04-22)
The isoprenoid pathway leads to various essential non-sterol products in insects. These end products have a crucial role in growth, differentiation, sexual maturation, and reproduction. 3-Hydroxy-3-me ...
Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: a promising strategy to regulate energy balance
(John Wiley & Sons, 2023)
Tackling the growing incidence and prevalence of obesity urgently requires uncovering new molecular pathways with therapeutic potential. The brain, and in particular the hypothalamus, is a major integrator ...