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CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity

Sierra, Adriana Y.; Gratacós, Esther; Carrasco, Patricia; Clotet, Josep; Ureña, Jesús; Serra, Dolors; Asins, Guillermina; Hegardt, Fausto G.; Casals Farré, Núria (Journal of Biological Chemistry, 2008)

CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the brain. The enzyme has recently been localized in neuron mitochondria. Although it has high sequence identity with ...

Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex

Mir, Joan Francesc; Zagmutt, Sebastián; Lichtenstein, Mathieu P.; García-Villoria, Judit; Weber, Minéia; Gracia, Ana; Fabriàs, Gemma; Casas, Josefina; López, Miguel; Casals Farré, Núria; Ribes, Antònia; Suñol, Cristina; Herrero, Laura; Serra, Dolors (Springer Nature, 2018)

Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of ghrelin action in hypothalamus. However, it ...