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The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
(Springer Nature, 2010)
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations ...
SIREs: searching for iron-responsive elements
(Oxford University Press, 2010-07)
The iron regulatory protein/iron-responsive element regulatory system plays a crucial role in the post-transcriptional regulation of gene expression and its disruption results in human disease. IREs are ...
Simulation methods with extended stability for stiff biochemical Kinetics
(Springer Nature, 2010)
Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical ...