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Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
(Advanced Healthcare Materials, 2015)
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa ...
Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016-02-01)
TGF-ß1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this ...
Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth
(Journal of Materials Science: Materials in Medicine, 2015-07-15)
This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical ...
All-in-one trifunctional strategy: a cell adhesive, bacteriostatic and bactericidal coating for titanium implants
(Colloids and Surfaces B: Biointerfaces, 2018-09)
Strategies to inhibit initial bacterial adhesion are extremely important to prevent infection on biomaterial surfaces. However, the simultaneous attraction of desired eukaryotic cells remains a challenge ...
A dual molecular biointerface combining RGD and KRSR sequences Improves osteoblastic functions by synergizing integrin and cell-membrane proteoglycan binding
(International Journal of Molecular Sciences, 2019-03-21)
This article belongs to the Special Issue Biomaterials for Musculoskeletal System
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Acta Biomaterialia, 2016-10-01)
Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ...
Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius
(Clinical Oral Implants Research, 2014-05-30)
Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ...
Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering
(Journal of Biomaterials Applications, 2015-03-23)
Nowadays, one of the main challenges in metal implants for bone substitution is the achievement of an elastic modulus close to that of human cortical bone as well as to provide an adequate interaction ...
Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
(Colloids and Surfaces B: Biointerfaces, 2019-04-24)
The lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome ...