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In vivo osteogenic potential of biomimetic hydroxyapatite/collagen microspheres: comparison with injectable cement pastes
(PLoS One, 2015-07-01)
The osteogenic capacity of biomimetic calcium deficient hydroxyapatite microspheres with and without collagen obtained by emulsification of a calcium phosphate cement paste has been evaluated in an in ...
Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
(Advanced Healthcare Materials, 2015)
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa ...
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Acta Biomaterialia, 2016-10-01)
Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ...
Characterization of ferrofluid-based stimuli-responsive elastomers
(Frontiers in Mechanical Engineering, 2016-12-12)
Stimuli-responsive materials undergo physicochemical and/or structural changes when a specific actuation is applied. They are heterogeneous composites, consisting of a non-responsive matrix where ...
Study on the use of 3‐aminopropyltriethoxysilane and 3‐chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti–Nb–Hf alloy
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014-06-09)
A biocompatible new titanium alloy Ti–16Hf–25Nb with low elastic modulus (45 GPa) and the use of short bioadhesive peptides derived from the extracellular matrix have been studied. In terms of cell ...
Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016-02-01)
TGF-ß1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this ...
Mechanical and microstructural characterization of new nickel-free low modulus beta-type titanium wires during thermomechanical treatments
(Materials Science and Engineering: A, 2015-06-11)
NiTi alloy is the only practical shape memory alloy (SMA) in biomedical use because of its excellent mechanical stability and functionality. However, it is estimated that between 4.5% and 28.5% of the ...
Development of tantalum scaffold for orthopaedic applications produced by space-holder method
(Materials & Design, 2015-10-15)
In the present study, production of tantalum porous scaffolds using the space holder technique was performed. The effect of size and content of sodium chloride particles, used as space holder, as well ...
Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
(Colloids and Surfaces B: Biointerfaces, 2019-04-24)
The lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome ...
Biological roles and delivery strategies for ions to promote osteogenic induction
(Frontiers in Cell and Developmental Biology, 2021-01-14)
Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ...