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Mostrando ítems 11-15 de 15
X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk
(Nature Research, 2013-08-09)
X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here,
we demonstrate a novel function of XIAP as a regulator of neurite outgrowth in neuronal ...
Feeding the brain: effect of nutrients on cognition, synaptic function, and AMPA receptors
(MDPI, 2022)
In recent decades, traditional eating habits have been replaced by a more globalized diet, rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary factors contribute ...
Soluble oligomers of amyloid-β peptide disrupt Membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction
(Elsevier, 2011-08-05)
β-Amyloid (Aβ), a peptide generated from the amyloid precursor protein, is widely believed to underlie the pathophysiology of Alzheimer disease (AD). Emerging evidences suggest that soluble Aβ oligomers ...
N-methyl-DD-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells
(Elsevier, 2006-03-10)
During the postnatal development of cerebellum, lack of excitatory innervation from the mossy fibers results in cerebellar granule cell (CGC) apoptosis during the migration of the cells toward the ...
To be or not to be a fat burner, that is the question for cpt1c in cancer cells
(Springer Nature, 2023)
There is an urgent need to identify reliable genetic biomarkers for accurate diagnosis, prognosis, and treatment of different tumor types. Described as a prognostic marker for many tumors is the neuronal ...