Now showing items 1-2 of 2

    • Astrocytes and oligodendrocytes in grey and white matter regions of the brain metabolize fatty acids 

      Hofmann, Kristina; Rodríguez-Rodríguez, Rosalía; Gaebler, Anne; Casals i Farré, Núria; Scheller, Anja; Kuerschner, Lars (Scientific Reports, 2017-09-07)
      The grey and white matter regions of the mammalian brain consist of both neurons and neuroglial cells. Among the neuroglia, the two macroglia oligodendrocytes and astrocytes are the most abundant cell ...
    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas Prat, Maria; Fadó, Rut; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan_, Shigeru; Solé, Montse; UNZETA, Mercedes; Miñano-Molina, Alfredo J; Rodriguez-Alvarez, Jose; Dickson, Eamonn; Casals, Nuria (Journal of Cell Biology, 2020)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...