Now showing items 1-4 of 4

    • Pomace olive oil concentrated in triterpenic acids restores vascular function, glucose tolerance and obesity progression in mice 

      Claro-Cala, Carmen Maria; Quintela, Jose Carlos; Pérez-Montero, Marta; Miñano, Javier; Alvarez de Sotomayor, María; Dolores Herrera, María; Rodríguez-Rodríguez, Rosalía (Nutrients, 2020-01)
      Pomace olive oil, an olive oil sub-product, is a promising source of bioactive triterpenoids such as oleanolic acid and maslinic acid. Considering the vascular actions of pomace olive oil and the potential ...
    • Reconfigurable multiplexed point of care system for monitoring type 1 diabetes patients 

      Márquez, Augusto; Aymerich, Joan; Dei, Michele; Rodríguez-Rodríguez, Rosalía; Vázquez-Carrera, Manuel; Pizarro-Delgado, Javier; Giménez-Gómez, Pablo; Merlos, Angel; Terés, Lluís (Biosensors and Bioelectronics, 2019-07)
      At the point of care (POC), on-side clinical testing allows fast biomarkers determination even in resource-limited environments. Current POC systems rely on tests selective to a single analyte or complex ...
    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas, Maria; Rut, Fadó; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan, Shigeru; Solé, Montse; Unzeta, Mercedes; Miñano Molina, Alfredo Jesús; Rodríguez-Álvarez, José; James Dickson, Eamonn; Casals i Farré, Núria (Journal of Cell Biology, 2020-09)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
    • Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth 

      Palomo Guerrero, Marta; Fadó Andrés, Rut; Casas, Maria; Pérez-Montero, Marta; Baena, Miguel; Helmer, Patrick O.; Domínguez, José Luis; Roig, Aina; Serra, Dolors; Hayen, Heiko; Stenmark, Harald; Raiborg, Camilla; Casals i Farré, Núria (eLife, 2019)
      Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty ...