Browsing Ciències de la Salut by Subject "Ferro"

Now showing items 1-5 of 5

    • Characterization of ferrofluid-based stimuli-responsive elastomers 

      De Pedro, Sandra; Muñoz-Berbel, Xavier; Rodríguez-Rodríguez, Rosalía; Sort, Jordi; Plaza, Jose Antonio; Brugger, Juergen; Llobera, Andreu; Cadarso, Victor J. (Frontiers in Mechanical Engineering, 2016-12-12)
      Stimuli-responsive materials undergo physicochemical and/or structural changes when a specific actuation is applied. They are heterogeneous composites, consisting of a non-responsive matrix where ...

    • Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype 

      Maus, Mate; López-Polo, Vanessa; Mateo, Lidia; Lafarga, Miguel; Aguilera, Mònica; De Lama, Eugenia; Meyer, Kathleen; Sola, Anna; Lopez-Martinez, Cecilia; López-Alonso, Ines; Guasch-Piqueras, Marc; Hernandez-Gonzalez, Fernanda; Chaib, Selim; Rovira, Miguel; Sanchez, Mayka; Faner, Rosa; Agusti, Alvar; Diéguez-Hurtado, Rodrigo; Ortega, Sagrario; Manonelles, Anna; Engelhardt, Stefan; Monteiro, Freddy; Stephan-Otto Attolini, Camille; Prats, Neus; Albaiceta, Guillermo; Cruzado, Josep M.; Serrano, Manuel (Nature Metabolism, 2023)
      Fibrogenesis is part of a normal protective response to tissue injury that can become irreversible and progressive, leading to fatal diseases. Senescent cells are a main driver of fibrotic diseases ...

    • Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins 

      Sanchez, Mayka; Galy, Bruno; Schwanhaeusser, Bjoern; Blake, Jonathon; Bähr-Ivacevic, Tomi; Benes, Vladimir; Selbach, Matthias; Muckenthaler, Martina U.; Hentze, Matthias W. (Blood, 2011)
      Iron regulatory proteins (IRPs) 1 and 2 are RNA-binding proteins that control cellular iron metabolism by binding to conserved RNA motifs called iron-responsive elements (IREs). The currently known ...

    • SIREs: searching for iron-responsive elements 

      Campillos, Monica; Cases, Ildefonso; Hentze, Matthias W.; Sanchez, Mayka (Nucleic Acids Research, 2010-07)
      The iron regulatory protein/iron-responsive element regulatory system plays a crucial role in the post-transcriptional regulation of gene expression and its disruption results in human disease. IREs are ...

    • The actin binding protein profilin 2 is a novel regulator of iron homeostasis 

      Luscieti, Sara; Galy, Bruno; Gutierrez, Lucia; Reinke, Michael; Couso, Jorge; Shvartsman, Maya; Di Pascale, Antonio; Witke, Walter; Hentze, Matthias W.; Pilo Boyl, Pietro; Sanchez, Mayka (Blood, 2017)
      Cellular iron homeostasis is controlled by the iron regulatory proteins (IRPs) 1 and 2 that bind cis-regulatory iron-responsive elements (IRE) on target messenger RNAs (mRNA). We identified profilin 2 ...