Browsing Ciències de la Salut by Subject "Fármacos"

Now showing items 1-3 of 3

    • Determining the value of two biologic drugs for chronic inflammatory skin diseases: results of a multi-criteria decision analysis 

      Zozaya, Néboa; Martínez-Galdeano, Lucía; Alcala, Bleric; Armario-Hita, Jose Carlos; Carmona, Concepción; Carrascosa, Jose Manuel; Herranz, Pedro; Lamas, María Jesús; Trapero Bertran, Marta; Hidalgo-Vega, Álvaro (BioDrugs, 2018)
      Background and Objective: Multi-criteria decision analysis (MCDA) is a tool that systematically considers multiple factors relevant to health decision-making. The aim of this study was to use an MCDA ...

    • Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance 

      Garcia-Chica, Jesús; Paraiso, West Kristian; Zagmutt, Sebastián; Fosch, Anna; Reguera, Ana Cristina; Alzina, Sara; Sánchez-García, Laura; Fukushima, Shigeto; Toh, Kazuko; Casals, Núria; Serra, Dolors; Herrero, Laura; Garcia Gomez, Jordi; Kataoka, Kazunori; Ariza, Xavier; Quader, Sabina; Rodriguez-Rodriguez, Rosalia (Biomaterials Science, 2023)
      Targeting brain lipid metabolism is a promising strategy to regulate the energy balance and fight metabolic diseases such as obesity. The development of stable platforms for selective delivery of drugs, ...

    • Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells 

      Page, Brent D.G.; Valerie, Nicholas C.K.; Wright, Roni H.G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlöf, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundbäck, Thomas; Scobie, Martin; Strömberg, Kia; Stenmark, Pål; Beato, Miguel; Helleday, Thomas (Nature Communications, 2018)
      With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...