Listando Ciències de la Salut por materia "ADN"
Mostrando ítems 1-6 de 6
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Aberrantly spliced mRNAs of the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene with a donor splice-site point mutation produce hereditary HL deficiency
(Journal of Lipid Research, 1996-11)A novel point mutation in the 3-hydroxy-3methyl-glutaryl coenzyme A lyase gene was found in a Turkish patient with homozygous 3-hydroxy-3-methylglutaric acidemia. Amplification by RT-PCR of the mRNA ... -
CDK-mediated Yku80 phosphorylation regulates the balance between non-homologous end joining (NHEJ) and homologous directed recombination (HDR)
(Journal of Molecular Biology, 2020)There are two major pathways for repairing DNA double-strand breaks (DSBs): homologous directed recombination (HDR) and non-homologous end-joining (NHEJ). While NHEJ functions throughout the cell cycle, ... -
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
(BMC Bioinformatics, 2010)Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, production and manipulations ... -
Nucleosome architecture throughout the cell cycle
(Scientific Reports, 2016-01-28)Nucleosomes provide additional regulatory mechanisms to transcription and DNA replication by mediating the access of proteins to DNA. During the cell cycle chromatin undergoes several conformational ... -
The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
(Genome Biology, 2010-06-23)Background: The G1-to-S transition of the cell cycle in the yeast Saccharomyces cerevisiae involves an extensive transcriptional program driven by transcription factors SBF (Swi4-Swi6) and MBF (Mbp1-Swi6). ... -
Unravelling the encapsulation of DNA and other biomolecules in HAp microcalcifications of human breast cancer tissues by raman imaging
(Cancers, 2021)Microcalcifications are detected through mammography screening and, depending on their morphology and distribution (BI-RADS classification), they can be considered one of the first indicators of suspicious ...