Browsing Ciències de la Salut by Author "UNZETA, Mercedes"

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    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas Prat, Maria; Fadó, Rut; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan_, Shigeru; Solé, Montse; UNZETA, Mercedes; Miñano-Molina, Alfredo J; Rodriguez-Alvarez, Jose; Dickson, Eamonn; Casals, Nuria (Journal of Cell Biology, 2020)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...