Now showing items 1-2 of 2

    • Genetic screening for TLR7 variants in young and previously healthy men with severe COVID-19 

      Solanich, Xavier; Vargas-Parra, Gardenia; Van der Made, Caspar I.; Simons, Annet; Schuurs-Hoeijmakers, Janneke; Antolí, Arnau; Del Valle, Jesús; Rocamora-Blanch, Gemma; Setién, Fernando; Esteller, Manel; Van Reijmersdal, Simon V.; Riera-Mestre, Antoni; Sabater-Riera, Joan; Capellà, Gabriel; Van de Veerdonk, Frank L.; Van der Hoven, Ben; Corbella Virós, Xavier; Hoischen, Alexander; Lázaro, Conxi (Frontiers in Immunology, 2021)
      Introduction: Loss-of-function TLR7 variants have been recently reported in a small number of males to underlie strong predisposition to severe COVID-19. We aimed to determine the presence of these rare ...
    • The impact of KRAS mutations on VEGF-A production and tumour vascular network 

      Figueras, Agnès; Arbós Vilà, Maria Antonia; Quiles Pérez, María Teresa; Viñals, Francesc; Germà, Josep Ramón; Capellà, Gabriel (BMC Cancer, 2013-03-18)
      Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ...