Browsing Ciències de la Salut by Issue Date

Now showing items 41-60 of 723

    • Polymeric additives to enhance the functional properties of calcium phosphate cements 

      Pérez Antoñanzas, Roman; Hae-Won, Kim; Ginebra Molins, Maria Pau (2012-03-20)
      The vast majority of materials used in bone tissue engineering and regenerative medicine are based on calcium phosphates due to their similarity with the mineral phase of natural bone. Among them, calcium ...

    • Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival 

      Barneda-Zahonero, Bruna; Servitja, Joan-Marc; Badiola, Nahuai; Miñano Molina, Alfredo Jesús; Fadó Andrés, Rut; Saura, Carlos A.; Rodríguez-Álvarez, José (Journal of Biological Chemistry, 2012-03-30)
      NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ...

    • Standardizing admission and discharge processes to improve patient flow: a cross sectional study 

      Ortiga Fontgivell, Berta; Salazar Soler, Albert; Jovell Fernández, Albert; Escarrabill, Joan; Marca, Guillem; Corbella Virós, Xavier (BMC Health Services Research, 2012-06-28)
      Background: The aim of this study was to evaluate how hospital capacity was managed focusing on standardizing the admission and discharge processes. Methods: This study was set in a 900-bed university ...

    • The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation 

      Ferrezuelo, Francisco; Colomina, Neus; Palmisano, Alida; Garí, Eloi; Gallego, Carme; Csikász-Nagy, Attila; Aldea Malo, Martí (Nature Communications, 2012-08-21)
      Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size ...

    • A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer 

      Margalef, Pol; Fernández-Majada, Vanessa; Villanueva, Alberto; Garcia-Carbonell, Ricard; Iglesias, Mar; López, Laura; Martínez-Iniesta, María; Villà-Freixa, Jordi; Mulero, Mari Carmen; Andreu, Montserrat; Torres, Ferran; Mayo, Marty W.; Bigas, Anna; Espinosa, Lluis (Cell Reports, 2012-10-25)
      Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ...

    • An effect of bilingualism on the auditory cortex 

      Ressel, Volker; Pallier, Christopher; Ventura-Campos, Noelia; Díaz Menéndez, Begoña; Roessler, Abeba; Ávila, César; Sebastián-Gallés, Núria (Journal of Neuroscience, 2012-11)
      Two studies (Golestani et al., 2007; Wong et al., 2008) have reported a positive correlation between the ability to perceive foreign speech sounds and the volume of Heschl's gyrus (HG), the structure ...

    • Multichannel functional testing in normal subjects, glaucoma suspects, and glaucoma patients 

      Antón López, Alfonso; Capilla, Pascual; Morilla Grasa, Antonio; Luque, María José; Artigas, José María; Felipe, Adelina (Investigative Ophthalmology & Visual Science, 2012-12)
      Purpose.: To evaluate visual function with a novel multichannel functional test named the ATD Multichannel Functional Test. Methods.: This multicenter study had a prospective and cross-sectional ...

    • Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis 

      Donadio, Márcio V.F.; De Souza, Guilherme C.; Tiecher, Gabriele; Heinzmann-Filho, João P.; Paim, Taísa F.; Hommerding, Patrícia X.; Marosticaf, Paulo J.C. (Jornal de Pediatria, 2013)
      Objective: To assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables. Methods: Children and adolescents diagnosed with CF, aged 6 to ...

    • Esperanza de vida entre 1991-2011: explicación epidemiológica a la desigualdad por género en Tarragona, una provincia de Cataluña, España 

      Gonzalvo-Cirac, Margarita; Girabent Farrés, Montserrat; Roqué Sánchez, María Victoria (Población y Salud en Mesoamérica, 2013)
      El objetivo de esta investigación es determinar si las distintas causas de muerte explicarían la desigualdad de la mortalidad por sexo entre 1991 y 2011 en la provincia de Tarragona (Cataluña, España) ...

    • Novel mutations in the ferritin-L iron-responsive element that only mildly impair IRP binding cause hereditary hyperferritinaemia cataract syndrome 

      Luscieti, Sara; Tolle, Gabriele; Aranda, Jessica; Benet Campos, Carmen; Risse, Frank; Morán, Érica; Muckenthaler, Martina U.; Sánchez, Mayka (Orphanet Journal of Rare Diseases, 2013)
      Background: Hereditary Hyperferritinaemia Cataract Syndrome (HHCS) is a rare autosomal dominant disease characterized by increased serum ferritin levels and early onset of bilateral cataract. The disease ...

    • Iron refractory iron deficiency anemia 

      De Falco, Luigia; Sanchez, Mayka; Silvestri, Laura; Kannengiesser, Caroline; Muckenthaler, Martina U.; Iolascon, Achille; Gouya, Laurent; Camaschella, Clara; Beaumont, Carole (Haematologica, 2013)
      Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6In vitro gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an ...

    • Complementary and alternative medicine in pediatric patients 

      Claret Teruel, G.; Alsina Casanova, Miguel; Huici Sánchez, Malka; Trenchs Sainz de la Maza, Victoria; Luaces Cubells, Carles (European Journal of Clinical Pharmacy Atención Farmacéutica, 2013)
      The objectives are to ascertain the use of Complementary and Alternative Medicine (CAM) in patients attending the Pediatric Emergency Department (PED) of a tertiary hospital, to describe the characteristics ...

    • Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation 

      Hernández-Ortega, Sara; Bru Rullo, Samuel; Ricco Pacheco, Natalia; Ramírez, Sara; Casals i Farré, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet Erra, Josep (Journal of Biological Chemistry, 2013-02)
      Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ...

    • The impact of KRAS mutations on VEGF-A production and tumour vascular network 

      Figueras, Agnès; Arbós Vilà, Maria Antonia; Quiles Pérez, María Teresa; Viñals, Francesc; Germà, Josep Ramón; Capellà, Gabriel (BMC Cancer, 2013-03-18)
      Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ...

    • X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk 

      Fadó Andrés, Rut; Moubarak, Rana S.; Miñano Molina, Alfredo Jesús; Barneda-Zahonero, Bruna; Valero, Jorge; Saura, Carlos A.; Moran, Julio; Comella, Joan X.; Rodríguez-Álvarez, José (Scientific Reports, 2013-08-09)
      X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here, we demonstrate a novel function of XIAP as a regulator of neurite outgrowth in neuronal ...

    • A quick diagnosis unit as an alternative to conventional hospitalization in a tertiary public hospital: a descriptive study 

      Sanclemente-Ansó, Carmen; Salazar Soler, Albert; Bosch, Xavier; Capdevila, Cristina; Vallano, Antoni; Català, Isabel; Fernandez‑Alarza, Antonio F.; Rosón-Hernández, Beatriz; Corbella Virós, Xavier (Polish Archives of Internal Medicine, 2013-09-24)
      Introduction: Reports indicate that a significant number of patients admitted to internal medicine units could be studied on an outpatient basis. Objectives: This article assesses a quick diagnosis unit ...

    • Word frequency cues word order in adults: cross-linguistic evidence 

      Gervain, Judit; Sebastián-Gallés, Núria; Diaz, Begoña; Laka, Itziar; Mazuka, Reiko; Yamane, Naoto; Nespor, Marina; Mehler, Jacques (Frontiers in Psychology, 2013-10-02)
      One universal feature of human languages is the division between grammatical functors and content words. From a learnability point of view, functors might provide entry points or anchors into the syntactic ...

    • Alternatives to conventional hospitalization for improving lack of access to inpatient beds: a 12-year cross-sectional analysis 

      Corbella Virós, Xavier; Ortiga Fontgivell, Berta; Juan, Antoni; Ortega, Nuria; Gomez-Vaquero, Carmen; Capdevila, Cristina; Bardes, Ignasi; Alonso, Gilberto; Ferre, Carles; Soler, Maria; Mañez, Rafael; Jaurrieta, Eduardo; Pujol, Ramón; Salazar Soler, Albert (Journal of Hospital Administration, 2013-12-17)
      Background/Objective: When hospitals cannot guarantee available hospital beds for inpatient admission, patients are exposed to prolonged waits, cancellations and diversions that negatively affect their ...

    • Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation 

      Le Dily, François; Bau, Davide; Pohl, Andy; Vicent, Guillermo P.; Serra, Francois; Soronellas, Daniel; Castellano, Giancarlo; Wright, Roni H.G.; Ballare, Cecilia; Filion, Guillaume; Marti-Renom, Marc A.; Beato, Miguel (Genes & Development, 2014)
      The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ...

    • Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom 

      Tzou, Wen-Shyong; Chu, Ying; Lin, Tzung-Yi; Hu, Chin-Hwa; Pai, Tun-Wen; Liu, Hsin-Fu; Lin, Han-Jia; Cases, Ildeofonso; Rojas, Ana; Sanchez, Mayka; You, Zong-Ye; Hsu, Ming-Wei (PLoS One, 2014)
      Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The ...