Browsing Ciències de la Salut by Issue Date
Now showing items 41-60 of 723
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Polymeric additives to enhance the functional properties of calcium phosphate cements
(2012-03-20)The vast majority of materials used in bone tissue engineering and regenerative medicine are based on calcium phosphates due to their similarity with the mineral phase of natural bone. Among them, calcium ... -
Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival
(Journal of Biological Chemistry, 2012-03-30)NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ... -
Standardizing admission and discharge processes to improve patient flow: a cross sectional study
(BMC Health Services Research, 2012-06-28)Background: The aim of this study was to evaluate how hospital capacity was managed focusing on standardizing the admission and discharge processes. Methods: This study was set in a 900-bed university ... -
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
(Nature Communications, 2012-08-21)Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size ... -
A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Cell Reports, 2012-10-25)Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ... -
An effect of bilingualism on the auditory cortex
(Journal of Neuroscience, 2012-11)Two studies (Golestani et al., 2007; Wong et al., 2008) have reported a positive correlation between the ability to perceive foreign speech sounds and the volume of Heschl's gyrus (HG), the structure ... -
Multichannel functional testing in normal subjects, glaucoma suspects, and glaucoma patients
(Investigative Ophthalmology & Visual Science, 2012-12)Purpose.: To evaluate visual function with a novel multichannel functional test named the ATD Multichannel Functional Test. Methods.: This multicenter study had a prospective and cross-sectional ... -
Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis
(Jornal de Pediatria, 2013)Objective: To assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables. Methods: Children and adolescents diagnosed with CF, aged 6 to ... -
Esperanza de vida entre 1991-2011: explicación epidemiológica a la desigualdad por género en Tarragona, una provincia de Cataluña, España
(Población y Salud en Mesoamérica, 2013)El objetivo de esta investigación es determinar si las distintas causas de muerte explicarían la desigualdad de la mortalidad por sexo entre 1991 y 2011 en la provincia de Tarragona (Cataluña, España) ... -
Novel mutations in the ferritin-L iron-responsive element that only mildly impair IRP binding cause hereditary hyperferritinaemia cataract syndrome
(Orphanet Journal of Rare Diseases, 2013)Background: Hereditary Hyperferritinaemia Cataract Syndrome (HHCS) is a rare autosomal dominant disease characterized by increased serum ferritin levels and early onset of bilateral cataract. The disease ... -
Iron refractory iron deficiency anemia
(Haematologica, 2013)Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6In vitro gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an ... -
Complementary and alternative medicine in pediatric patients
(European Journal of Clinical Pharmacy Atención Farmacéutica, 2013)The objectives are to ascertain the use of Complementary and Alternative Medicine (CAM) in patients attending the Pediatric Emergency Department (PED) of a tertiary hospital, to describe the characteristics ... -
Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation
(Journal of Biological Chemistry, 2013-02)Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ... -
The impact of KRAS mutations on VEGF-A production and tumour vascular network
(BMC Cancer, 2013-03-18)Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ... -
X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk
(Scientific Reports, 2013-08-09)X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here, we demonstrate a novel function of XIAP as a regulator of neurite outgrowth in neuronal ... -
A quick diagnosis unit as an alternative to conventional hospitalization in a tertiary public hospital: a descriptive study
(Polish Archives of Internal Medicine, 2013-09-24)Introduction: Reports indicate that a significant number of patients admitted to internal medicine units could be studied on an outpatient basis. Objectives: This article assesses a quick diagnosis unit ... -
Word frequency cues word order in adults: cross-linguistic evidence
(Frontiers in Psychology, 2013-10-02)One universal feature of human languages is the division between grammatical functors and content words. From a learnability point of view, functors might provide entry points or anchors into the syntactic ... -
Alternatives to conventional hospitalization for improving lack of access to inpatient beds: a 12-year cross-sectional analysis
(Journal of Hospital Administration, 2013-12-17)Background/Objective: When hospitals cannot guarantee available hospital beds for inpatient admission, patients are exposed to prolonged waits, cancellations and diversions that negatively affect their ... -
Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
(Genes & Development, 2014)The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ... -
Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom
(PLoS One, 2014)Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The ...