Browsing Ciències de la Salut by Title

Now showing items 654-673 of 723

    • The impact of KRAS mutations on VEGF-A production and tumour vascular network 

      Figueras, Agnès; Arbós Vilà, Maria Antonia; Quiles Pérez, María Teresa; Viñals, Francesc; Germà, Josep Ramón; Capellà, Gabriel (BMC Cancer, 2013-03-18)
      Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ...

    • The influence of education on the access tochildhood immunization: the case of Spain 

      Mora Corral, Antoni J.; Trapero Bertran, Marta (BMC Public Health, 2018)
      Background: In order to enhance childhood vaccination uptake and the health consequences for the whole society, there is a need to study predictors that might help in understanding parents’ behaviour ...

    • The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2 

      Riley, Lisa G.; Heeney, Matthew M.; Rudinger-Thirion, Joëlle; Frugier, Magali; Campagna, Dean R.; Zhou, Ronghao; Hale, Gregory A.; Hilliard, Lee M.; Kaplan, Joel A.; Kwiatkowski, Janet L.; Sieff, Colin A.; Steensma, David P.; Rennings, Alexander J.; Simons, Annet; Schaap, Nicolaas; Roodenburg, Richard J.; Kleefstra, Tjitske; Arenillas, Leonor; Fita-Torró, Josep; Ahmed, Rasha; Abboud, Miguel; Bechara, Elie; Farah, Roula; Tamminga, Rienk Y. J.; Bottomley, Sylvia S.; Sanchez, Mayka; Huls, Gerwin; Swinkels, Dorine W.; Christodoulou, John; Fleming, Mark D. (Haematologica, 2018)
      variants have previously been described in patients with myopathy, lactic acidosis and sideroblastic anemia 2 (MLASA2). encodes the mitochondrial tyrosyl-tRNA synthetase, which is responsible for ...

    • The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage 

      Truman, Andrew W.; Kristjansdottir, Kolbrun; Wolfgeher, Donald; Ricco Pacheco, Natalia; Mayampurath, Anoop; Volchenboum, Samuel L.; Clotet Erra, Josep; Kron, Stephen J. (Data in Brief, 2015-03)
      The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. Here we show the results of applied quantitative affinity-purification ...

    • The relationship between performance and asymmetries in different multidirectional sprint tests in soccer players 

      Fílter, Alberto; Beltrán-Garrido, Vicente; Dos'Santos, Thomas; Romero-Rodríguez, Daniel; Requena, Bernardo; Loturco, Irineu; Madruga-Parera, Marc (Journal of Human Kinetics, 2021)
      Practitioners usually include change of direction (COD) and linear speed measurements in the testing batteries of soccer players; however, despite being a commonly occurring action, curve sprint (CS) ...

    • The return of malonyl-CoA to the brain: cognition and other stories 

      Fadó Andrés, Rut; Rodríguez-Rodríguez, Rosalía; Casals i Farré, Núria (Progress in Lipid Research, 2021-01)
      Nutrients, hormones and the energy sensor AMP-activated protein kinase (AMPK) tightly regulate the intracel-lular levels of the metabolic intermediary malonyl-CoA, which is a precursor of fatty ...

    • The role of gender and age in the emotional well-being outcomes of young adults 

      López-Madrigal, Claudia; de la Fuente, Jesús; García-Manglano, Javier; Martínez-Vicente, José Manuel; Peralta-Sánchez, Francisco Javier; Amate-Romera, Jorge (International Journal of Environmental Research and Public Health, 2021)
      Young adults face different stressors in their transition to college. Negative emotions such as stress can emerge from the demands they face. This study aimed at gaining an improved understanding of the ...

    • The role of perceived dignity and control in the wish to hasten death among advanced cancer patients: A mediation model 

      Monforte Royo, Cristina; Crespo, Iris; Rodríguez Prat, Andrea; Marimon Viadiu, Frederic; Porta Sales, Josep; Balaguer Santamaría, Albert (Psycho-Oncology, 2018-09-24)
      Objective: To test a model in which perceived loss of dignity and control are proposed, along with symptoms of depression and functional impairment, as risk factors for the wish to hasten death (WTHD) ...

    • The severity of hypoxic-ischemic encephalopathy correlates with multiple organ dysfunction in the hypothermia era 

      Alsina Casanova, Miguel; Martín-Ancel, Ana; Alarcon-Allen, Ana; Arca, Gemma; Gayá, Francisco; García-Alix, Alfredo (Pediatric Critical Care Medicine, 2017)
      Objectives: The objectives are to 1) determine whether there is a positive correlation between the severity of hypoxic-ischemic encephalopathy and multiple organ dysfunction and 2) evaluate the organ ...

    • The thrombotic risk in Cushing’s syndrome—questions, answers, and the algorithm to consider in its assessment: part I—thrombotic risk not related to surgery 

      Bryk-Wiązania, Agata Hanna; Minasyan, Mari; Świątkowska-Stodulska, Renata; Undas, Anetta; Hubalewska-Dydejczyk, Alicja; Webb, Susan M.; Valassi, Elena; Gilis-Januszewska, Aleksandra (Frontiers in Endocrinology, 2024)
      Introduction: Recently, it has been reported that there is a great diversity in strategies used for thromboprophylaxis in patients with Cushing’s syndrome (CS). An aim of this review was to discuss these ...

    • The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle 

      Ferrezuelo, Francisco; Colomina, Neus; Futcher, Bruce; Aldea Malo, Martí (Genome Biology, 2010-06-23)
      Background: The G1-to-S transition of the cell cycle in the yeast Saccharomyces cerevisiae involves an extensive transcriptional program driven by transcription factors SBF (Swi4-Swi6) and MBF (Mbp1-Swi6). ...

    • The use of simulation in nursing education programs: a cross-sectional interuniversity study 

      Chabrera, C.; Aldomà, M.; Bazo-Hernández, L.; Faro, M.; Farrés-Tarafa, M.; Gil-Mateu, E.; Gómez-Ibáñez, R.; Insa, E.; Medel, D.; Peñataro-Pintado, E.; Puiggrós-Binefa, A.; Rascón, C.; Sarria-Guerrero, J. A.; Ricart, M.; Suris, C.; Fernández, P.; Rodríguez-Higueras, Encarna (Hindawi, 2024)
      Background. Simulation-based education has been incorporated into nursing curricula as an educational strategy. However, its implementation has not yet been standardized in different regions. Purpose. ...

    • The validity and reliability of a novel app for the measurement of change of direction performance 

      Balsalobre-Fernández, Carlos; Bishop, Chris; Beltrán-Garrido, José Vicente; Cecilia-Gallego, Pau; Cuenca-Amigó, Aleix; Romero-Rodríguez, Daniel; Madruga-Parera, Marc (Journal of Sports Sciences, 2019)
      The aim of the present investigation was to analyze the validity and reliability of a novel iPhone app (CODTimer) for the measurement of total time and interlimb asymmetry in the 5 + 5 change of direction ...

    • Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype 

      Adams, Paul; Altes, Albert; Brissot, Pierre; Butzeck, Barbara; Cabantchik, Ioav; Cançado, Rodolfo; Distante, Sonia; Evans, Patricia; Evans, Robert; Ganz, Tomas; Girelli, Domenico; Hultcrantz, Rolf; McLaren, Gordon; Marris, Ben; Milman, Nils; Nemeth, Elizabeta; Nielsen, Peter; Pineau, Brigitte; Piperno, Alberto; Porto, Graça; Prince, Dianne; Ryan, John; Sanchez, Mayka; Santos, Paulo; Swinkels, Dorine; Teixeira, Emerência; Toska, Ketil; Vanclooster, Annick; White, Desley; Contributors and Hemochromatosis International Taskforce (Hepatology International, 2018)
      Although guidelines are available for hereditary hemochromatosis, a high percentage of the recommendations within them are not shared between the different guidelines. Our main aim is to provide an ...

    • Therapeutically relevant aspects in bone repair and regeneration 

      Antoñanzas Perez, Roman; Seo, Seog-Jin; Won, Jong-Eun; Lee, Eun-Jung; Jang, Jun-Hyeog; Knowles, Jonathan C.; Kim, Hae-Won (Materials Today, 2015-12)
      Over the past few years, attention has been focused on the therapeutic roles in designing bone scaffolds for successful repair and regeneration. Indeed, biologically dynamic events in the bone healing ...

    • Thermal and current flow effects of a capacitive–resistive electric transfer application protocol on chronic elbow tendinopathy. A cadaveric study 

      López-de-Celis, Carlos; Rodríguez-Sanz, Jacobo; Hidalgo García, César; Cedeño, Simón A; Zegarra Chávez, Daniel; Fanlo Mazas, Pablo; Albert, Pérez-Bellmunt (International Journal of Environmental Research and Public Health, 2021)
      Lateral elbow tendinopathy, or “tennis elbow,” is a pathology that affects around 1.3% of the general population. Capacitive–resistive electric transfer therapy aims to provoke temperature and current ...

    • Thermal and non-thermal effects of capacitive–resistive electric transfer application on different structures of the knee: a cadaveric study 

      Rodríguez-Sanz, Jacobo; Pérez Bellmunt, Albert; López de Celis, Carlos; Lucha-López, María Orosia; González Rueda, Vanessa; Tricás-Moreno, José Miguel; Simon, Mathias; Hidalgo-García, César (Scientific Reports, 2020)
      Capacitive–resistive electric transfer therapy is used in physical rehabilitation and sports medicine to treat muscle, bone, ligament and tendon injuries. The purpose is to analyze the temperature change ...

    • Three dimensional porous scaffolds derived from collagen, elastin and fibrin proteins orchestrate adipose tissue regeneration 

      Sawadkar, Prasad; Mandakhbayar, Nandin; Patel, Kapil D.; Olmas Buitrago, Jennifer; Hyun Kim, Tae; Rajasekar, Poojitha; Lali, Ferdinand; Kyriakidis, Christos; Rahmani, Benyamin; Mohanakrishnan, Jeviya; Dua, Rishbha; Greco, Karin; Lee, Jung-Hwan; Kim, Hae-Won; Knowles, Jonathan C.; García-Gareta, Elena (Journal of Tissue Engineering, 2021)
      Current gold standard to treat soft tissue injuries caused by trauma and pathological condition are autografts and off the shelf fillers, but they have inherent weaknesses like donor site morbidity, ...

    • Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study 

      Rubio-Palau, Josep; COVIDSurg Collaborative; GlobalSurg Collaborative (Anaesthesia, 2021)
      Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 ...

    • Tirbanibulina: revisión de su mecanismo de acción novedoso y de cómo encaja en el tratamiento de la queratosis actínica 

      Gilaberte, Y.; Fernández-Figueras, María-Teresa (Actas Dermo-Sifiliográficas, 2021)
      La queratosis actínica (QA) es una afección cutánea caracterizada por la proliferación de queratinocitos mutados que pueden convertirse en carcinoma escamoso cutáneo. Las terapias disponibles, aunque ...