Browsing Ciències de la Salut by Title

Now showing items 437-456 of 723

    • Missense SLC25A38 variations play an important role in autosomal recessive inherited sideroblastic anemia 

      Kannengiesser, Caroline; Sanchez, Mayka; Sweeney, Marion; Hetet, Gilles; Kerr, Briedgeen; Moran, Erica; Fuster Soler, Jose L.; Maloum, Karim; Matthes, Thomas; Oudot, Caroline; Lascaux, Axelle; Pondarré, Corinne; Sevilla Navarro, Julian; Vidyatilake, Sudharma; Beaumont, Carole; Grandchamp, Bernard; May, Alison (Haematologica, 2011)
      Congenital sideroblastic anemias are rare disorders with several genetic causes; they are characterized by erythroblast mitochondrial iron overload, differ greatly in severity and some occur within a ...

    • MMPs/TIMPs and inflammatory signalling de‐regulation in human incisional hernia tissues 

      Guillem Martí, Jordi; Diaz, Ramon; Quiles Pérez, María Teresa; Lopez‐Cano, Manuel; Vilallonga, Ramon; Huguet, Pere; Ramon‐y‐Cajal, Santiago; Sanchez‐Niubo, Albert; Reventós, Jaume; Armengol Carrasco, Manuel; Arbós Vilà, Maria Antonia (Journal of Cellular and Molecular Medicine, 2009-03-04)
      Incisional hernia is a common and important complication of laparotomies. Epidemiological studies allude to an underlying biological cause, at least in a subset of population. Interest has mainly focused ...

    • Mobility Difficulties, Physical Activity, and All-cause Mortality Risk in a Nationally representative Sample of Older Adults 

      Olaya, Beatriz; moneta, maria victoria; Domènech Abella, Joan; Miret, Marta; Bayés Marín, Ivet; Bayés Marín, Ivet; Ayuso-Mateos, Jose Luis; Haro, Josep Maria (The journals of gerontology. Series A, Biological sciences and medical sciences, 2018)
      This study sought to determine the association between levels of physical activity and mobility difficulties and time to death while accounting for the effect of several confounders. We also examined ...

    • Model to predict risk for hospital admission and indicate the safety of reverse triage in a hospital emergency department: A prospective validation study 

      Leey-Echavarría, Connie; Zorrilla-Riveiro, José; Arnau, Anna; Fernàndez-Puigbó, Mireia; Sala-Barcons, Ester; Gené, Emili (2022)
      To prospectively validate a model to predict hospital admission of patients given a low-priority classification on emergency department triage and to indicate the safety of reverse triage. Material ...

    • Modified shuttle test distance correlates with peak oxygen uptake in children and adolescents with severe therapy-resistant asthma 

      Schiwe, Daniele; Heinzmann-Filho, João Paulo; Silva Schindel, Cláudia; Fátima Gheller, Mailise; Evangelista Campos, Natália; Márcio Pitrez, Paulo; Fagundes Donadio, Márcio Vinícius (Frontiers in Physiology, 2019)
      Introduction: Several tests may be used to assess exercise intolerance in severe therapy-resistant asthma (STRA), including the gold standard cardiopulmonary exercise test (CPET) and the modified shuttle ...

    • Modulation of macrophage response by copper and magnesium ions in combination with low concentrations of dexamethasone 

      Díez-Tercero, Leire; Delgado, Luis M.; Antoñanzas Perez, Roman (Biomedicines, 2022)
      Macrophages have been deemed crucial for correct tissue regeneration, which is a complex process with multiple overlapping phases, including inflammation. Previous studies have suggested that divalent ...

    • Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016 

      González-Sanz, Rubén; Casas-Alba, Didac; Launes, Cristian; Muñoz-Almagro, Carmen; Ruiz-García, María Montserrat; Alonso, Mercedes; González-Abad, María José; Megías, Gregoria; Rabella, Nuria; Del Cuerpo, Margarita; Gozalo Margüello, Mónica; González-Praetorius, Alejandro; Martínez-Sapiña, Ana; Goyanes-Galán, María José; Romero, María Pilar; Calvo, Cristina; Antón, Andrés; Imaz, Manuel; Aranzamendi, Maitane; Hernández-Rodríguez, Águeda; Moreno-Docón, Antonio; Rey-Cao, Sonia; Navasués, Ana; Otero, Almudena; Cabrerizo, María (Eurosurveillance, 2019-02)
      Enterovirus 71 (EV-A71) is a small, non-enveloped, single-stranded RNA virus that belongs to the species Enterovirus A along with 24 other serotypes within the Enterovirus genus [1]. According to the ...

    • Molecular evolution of multiple-level control of heme biosynthesis pathway in animal kingdom 

      Tzou, Wen-Shyong; Chu, Ying; Lin, Tzung-Yi; Hu, Chin-Hwa; Pai, Tun-Wen; Liu, Hsin-Fu; Lin, Han-Jia; Cases, Ildeofonso; Rojas, Ana; Sanchez, Mayka; You, Zong-Ye; Hsu, Ming-Wei (PLoS One, 2014)
      Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The ...

    • Motor rehabilitation after stroke: European Stroke Organisation (ESO) consensus-based definition and guiding framework 

      Kwakkel, Gert; Stinear, Cathy; Essers, Bea; Munoz-Novoa, Maria; Branscheidt, Meret; Cabanas-Valdés, Rosa; Lakičević, Sandra; Lampropoulou, Sofia; Luft, Andreas R.; Marque, Philippe; Moore, Sarah A.; Solomon, John M.; Swinnen, Eva; Turolla, Andrea; Alt Murphy, Margit; Verheyden, Geert (European Stroke Journal, 2023)
      Purpose: To propose a consensus-based definition and framework for motor rehabilitation after stroke. Methods: An expert European working group reviewed the literature, attaining internal consensus after ...

    • Multichannel functional testing in normal subjects, glaucoma suspects, and glaucoma patients 

      Antón López, Alfonso; Capilla, Pascual; Morilla Grasa, Antonio; Luque, María José; Artigas, José María; Felipe, Adelina (Investigative Ophthalmology & Visual Science, 2012-12)
      Purpose.: To evaluate visual function with a novel multichannel functional test named the ATD Multichannel Functional Test. Methods.: This multicenter study had a prospective and cross-sectional ...

    • Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona, Spain 

      Mañá, Juan; Rubio-Rivas, Manuel; Villalba, Nadia; Marcoval, Joaquim; Iriarte, Adriana; Molina-Molina, María; Llatjos, Roger; García, Olga; Martínez-Yélamos, Sergio; Vicens-Zygmunt, Vanessa; Gámez, Cristina; Pujol, Ramón; Corbella Virós, Xavier (Medicine, 2017-07)
      Cohort studies of large series of patients with sarcoidosis over a long period of time are scarce. The aim of this study is to report a 40-year clinical experience of a large series of patients at ...

    • Multidisciplinary preventive intervention for breast cancer-related lymphedema: an international consensus 

      Martínez-Jaimez, Patricia; Fuster-Linares, Pilar; Piller, Neil; Masia, Jaume; Yamamoto, Takumi; López Montoya, Luis Enrique; Monforte-Royo, Cristina (European Journal of Cancer Care, 2022)
      Objective: To establish a consensus regarding the multidisciplinary prevention of breast cancer-related lymphedema (BCRL), taking into account the expert opinion of professional groups from across the ...

    • Multidisciplinary preventive intervention for breast cancer-related lymphedema: an international consensus 

      Martínez-Jaimez, Patricia; Fuster-Linares, Pilar; Piller, Neil; Masia, Jaume; Yamamoto, Takumi; López Montoya, Luis Enrique; Monforte-Royo, Cristina (Wiley, 2022)
      Objective: To establish a consensus regarding the multidisciplinary prevention of breast cancer-related lymphedema (BCRL), taking into account the expert opinion of professional groups from across the ...

    • Multimorbidity patterns in low-middle and high income regions: a multiregion latent class analysis using ATHLOS harmonised cohorts 

      Bayés Marín, Ivet; Sanchez-Niubo, Albert; Egea Cortés, Laia; Nguyen, Hai; Prina, Matthew; Fernández, Daniel; Haro, Josep Maria; Olaya, Beatriz (BMJ Publishing Group, 2020)
      Our aim was to determine clusters of non-communicable diseases (NCDs) in a very large, population-based sample of middle-aged and older adults from low- and middle-income (LMICs) and high-income (HICs) ...

    • Multiorgan dysfunction in infants of 33-35 weeks gestation with severe hypoxic-ischemic encephalopathy treated with hypothermia anatomy & physiology 

      Alsina Casanova, Miguel; Martín Ancel, Ana; León Lozano, Marisol; Arca Díaz, Gemma; Pérez Fernández, Elia; García Alix, Alfredo (Anatomy & Physiology: Current Research, 2018)
      Background: The benefits of hypothermia on neurodevelopment of newborns ≥ 36 weeks gestation with hypoxicischemic encephalopathy have been shown in large clinical trials. The security of hypothermia in ...

    • Multiple drug regimen-refractory rosai–dorfman–destombes disease mimicking relapsing polychondritis successfully treated with cobimetinib 

      López-Aldabe, Kima; Escrihuela-Vidal, Francesc; Tuells, Manel; Llobera-Ris, Clàudia; Bauer Alonso, Andrea; CORTES-ROMERA, MONTSERRAT; Gràcia-Sànchez, Laura; Tormo-Ratera, Marian; Juanola Roura, Xavier; Penin-Mosquera, Rosa Maria; Corbella Virós, Xavier; Solanich, Xavier (European Journal of Case Reports in Internal Medicine, 2022)
      Rosai-Dorfman-Destombes disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare non-Langerhans cell histiocytosis of unknown cause. The disease often manifests as bilateral painless ...

    • Multiplex antibody analysis of IgM, IgA and IgG to SARS-CoV-2 in saliva and serum from infected children and their close contacts 

      Dobaño, Carlota; Alonso, Selena; Vidal, Marta; Jiménez, Alfons; Rubio, Rocío; Santano, Rebeca; Barrios, Diana; Pons Tomas, Gemma; Melé Casas, María; Hernández García, María; Girona-Alarcón, Mònica; Puyol, Laura; Baro, Barbara; Millat-Martínez, Pere; Ajanovic, Sara; Balanza, Núria; Arias, Sara; Rodrigo Melero, Natalia; Carolis, Carlo; García-Miquel, Aleix; Bonet-Carné, Elisenda; Claverol, Joana; Cubells, Marta; Fortuny, Claudia; Fumadó, Victoria; Codina, Anna; Bassat, Quique; Muñoz-Almagro, Carmen; Fernández de Sevilla, Mariona; Gratacós, Eduard; Izquierdo, Luis; García-García, Juan José; Aguilar, Ruth; Jordan, Iolanda; Moncunill, Gemma (Frontiers in Immunology, 2022)
      COVID-19 affects children to a lesser extent than adults but they can still get infected and transmit SARS-CoV-2 to their contacts. Field deployable non-invasive sensitive diagnostic techniques are ...

    • Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III 

      Hernández, Gonzalo; Romero-Cortadellas, Lídia; Ferrer-Cortès, Xènia; Venturi, Veronica; Dessy-Rodriguez, Mercedes; Olivella, Mireia; Husami, Ammar; Pérez De Soto, Concepción; Morales-Camacho, Rosario M.; Villegas, Ana; González-Fernández, Fernando-Ataulfo; Morado, Marta; Kalfa, Theodosia A.; Quintana-Bustamante, Oscar; Pérez-Montero, Santiago; Tornador, Cristian; Segovia, Jose-Carlos; Sánchez, Mayka (Haematologica, 2023)
      Congenital dyserythropoietic anemia type III (CDA III) is one of the rarest types of CDA. The autosomal dominant form of CDA III, is due to mono-allelic mutations in the KIF23 gene (MIM:105600); two ...

    • Müller glia fused with adult stem cells undergo neural differentiation in human retinal models 

      Bonilla-Pons, Sergi Àngel; Nakagawa, Shoma; Garreta Bahima, Elena; Fernández-Blanco, Álvaro; Pesaresi, Martina; D'Antin, Justin Christopher; Perez, Ruben Sebastian; Greco, Daniela; Domínguez-Sala, Eduardo; Gómez-Riera, Raúl; Barraquer Compte, Rafael Ignacio; Dierssen, Mara; Pulido, Nuria Montserrat; Cosma, Maria Pia (eBioMedicine, 2022)
      Background: Visual impairments are a critical medical hurdle to be addressed in modern society. Müller glia (MG) have regenerative potential in the retina in lower vertebrates, but not in mammals. ...

    • MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast transdifferentiation 

      Bisceglie, Lavinia; Hopp, Ann-Katrin; Gunasekera, Kapila; Wright, Roni H.G.; Le Dily, François; Vidal, Enrique; Dall'Agnese, Alessandra; Caputo, Luca; Nicoletti, Chiara; Puri, Pier Lorenzo; Beato, Miguel; Hottiger, Michael O. (iScience, 2021)
      While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation ...