Browsing Ciències de la Salut by Title

Now showing items 321-340 of 723

    • High-dose methylprednisolone pulses for 3 days vs. low-dose dexamethasone for 10 days in severe, non-critical COVID-19: a retrospective propensity score matched analysis 

      Mora-Luján, José María; Tuells, Manel; Montero, Abelardo; Formiga, Francesc; Homs, Narcís A.; Albà-Albalate, Joan; Corbella Virós, Xavier; Rubio-Rivas, Manuel (Journal of Clinical Medicine, 2021)
      Corticosteroids are largely recommended in patients with severe COVID-19. However, evidence to support high-dose methylprednisolone (MP) pulses is not as robust as that demonstrated for low-dose ...

    • High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial 

      Fernandez, Rafael; Subirà Cuyàs, Carles; Frutos‑Vivar, Fernando; Rialp, Gemma; Laborda, Cesar; Masclans, Joan Ramon; Lesmes, Amanda; Panadero, Luna; Hernandez, Gonzalo (Annals of Intensive Care, 2017-05-02)
      Background: Extubation failure is associated with increased morbidity and mortality, but cannot be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation respiratory failure ...

    • High-intensity vs. sham inspiratory muscle training in patients with chronic heart failure: a prospective randomized trial 

      Marco, Ester; Ramírez-Sarmiento, Alba L; Coloma, Ana; Sartor, Monique; Comin-Colet, Josep; Vila, Joan; Enjuanes, Cristina; Bruguera, Jordi; Escalada, Ferran; Gea, Joaquim; Orozco-Levi, Mauricio (European Journal of Heart Failure, 2014)
      Aims: The purpose of this study was to evaluate the effectiveness, feasibility, and safety of a 4-week high-intensity inspiratory muscle training (hi-IMT) in patients with chronic heart failure (CHF). ...

    • Hip range of motion and strength in male athletes with stage 1 osteitis pubis: a cross-sectional and correlational study 

      Ceballos-Laita, Luis; Hernando-Garijo, Ignacio; Medrano-de-la-Fuente, Ricardo; Mingo-Gómez, Maria Teresa; Carrasco-Uribarren, Andoni; Jiménez, Sandra (International Journal of Environmental Reseacrh and Public Health, 2022)
      Background: The objectives of this study were: (1) to determine whether athletes with stage 1 osteitis pubis (OP) present differences in hip range of motion (ROM) and muscle strength, between both sides ...

    • Histological comparison of in vitro and in vivo development of peripheral posterior capsule opacification in human donor tissue 

      Ribeiro Koch, Camila; D'Antin, Justin Christopher; Tresserra, Francisco; Barraquer, Rafael Ignasi; Michael, Ralph (Experimental Eye Research, 2019)
      In order to study the mechanisms involved in the development of posterior capsule opacification (PCO) we compared in vivo developed PCO with PCO formed in tissue culture with focus on the periphery of ...

    • Hormone-control regions mediate steroid receptor–dependent genome organization 

      Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo P.; Carbonell-Caballero, José; Sharma, Priyanka; Villanueva-Cañas, José Luis; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni H.G.; Beato, Miguel (Genome Research, 2019)
      In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...

    • How did the COVID-19 lockdown affect children and adolescent's well-being: spanish parents, children, and adolescents respond 

      Ajanovic, Sara; Garrido-Aguirre, Jon; Baro, Bàrbara; Balanza, Núria; Varo, Rosauro; Millat-Martínez, Pere; Arias, Sara; Fonollosa, Jordi; Perera-Lluna, Alexandre; Jordan, Iolanda; Muñoz-Almagro, Carmen; Bonet-Carne, Elisenda; Crosas-Soler, Aina; Via, Esther; Nafria, Begonya; García-García, Juan José; Bassat, Quique (Frontiers in Public Health, 2021)
      Background: During the COVID-19 pandemic, lockdown strategies have been widely used to contain SARS-CoV-2 virus spread. Children and adolescents are especially vulnerable to suffering psychological ...

    • How do sports injury epidemiological outcomes vary depending on athletes' response rates to a weekly online questionnaire? An analysis of 39-week follow-up from 391 athletics (track and field) athletes 

      Edouard, Pascal; Dandrieux, Pierre-Eddy; Blanco de Tena Davila, David; Tondut, Jeanne; Chapon, Joris; Navarro, Laurent; Junge, Astrid; Hollander, Karsten (Scandinavian Journal of Medicine & Science in Sports, 2024)
      Objective: To explore how sports injury epidemiological outcomes (i.e., prevalence, average prevalence, incidence, burden, and time to first injury) vary depending on the response rates to a weekly ...

    • How has the strict lockdown during the SARS-COV-2 outbreak changed the diet of Spaniards? 

      Mora, Toni; Fichera, Eleonora; Lopez-Valcarcel, Beatriz G. (SSM - Population Health, 2023)
      Purpose: We investigate the impact of a specific macroeconomic shock that occurred as a response to the SARS-COV-2 outbreak, namely the strict lockdown imposed in Spain on the March 14, 2020. Methods: ...

    • Human immunodeficiency virus/hepatits C virus coinfection in Spain: elimination Is feasible, but the burden of residual cirrhosis will be significant 

      Berenguer, Juan; Jarrín, Inmaculada; Pérez-Latorre, Leire; Hontañón, Víctor; Vivancos, María J.; Navarro, Jordi; Téllez, María J.; Guardiola Tey, Josep Maria; Iribarren, José A.; Rivero-Juárez, Antonio; Márquez, Manuel; Artero, Arturo; Morano, Luis; Santos, Ignacio; Moreno, Javier; Fariñas, María C.; Galindo, María J.; Hernando, María A.; Montero, Marta; Cifuentes, Carmen; Domingo, Pere; Sanz, José; Domíngez, Lourdes; Ferrero, Oscar L.; De la Fuente, Belén; Rodríguez, Carmen; Reus, Sergio; Hernández-Quero, José; Gaspar, Gabriel; Pérez-Martínez, Laura; García, Coral; Force, Lluis; Veloso, Sergio; Losa, Juan E.; Vilaró, Josep; Bernal, Enrique; Arponen, Sari; Ortí, Amat J.; Chocarro, Ángel; Teira, Ramón; Alonso, Gerardo; Silvariño, Rafael; Vegas, Ana; Geijo, Paloma; Bisbe, Josep; Esteban, Herminia; González-García, Juan; GeSIDA 8514 Study Group (Open Forum Infectious Diseases, 2018-01)
      Background: We assessed the prevalence of antibodies against hepatitis C virus (HCV-Abs) and active HCV infection in patients infected with human immunodeficiency virus (HIV) in Spain in 2016 and compared ...

    • Humo de tercera mano y otros retos del control del tabaquismo en población pediátrica 

      Lidón Moyano, Cristina; Díez-Izquierdo, Ana; Martínez Sánchez, Jose María (Anales de Pediatría, 2020)

    • Hydrops fetalis caused by congenital syphilis: an ancient disease? 

      Ramis Fernández, Sofía Martina; Alsina-Casanova, Miguel; Herranz-Barbero, Ana; Aldecoa-Bilbao, Victoria; Borràs-Novell, Cristina; Salvia-Roges, Dolors (International Journal of STD & AIDS, 2019)
      Syphilis is currently an emerging health problem, especially in high-income countries. Infection rates have increased significantly in European countries such as the United Kingdom and Spain in the last ...

    • Hymenal tags of the newborn 

      Di Candia, Angela; Silecchia, Valeria; Valerio, Enrico; Furcolo, Giuseppe; Palatron, Silvia; Cutrone, Mario; Grimalt Santacana, Ramon (Journal of Dermatological Research, 2019)
      Evaluation of female newborn genitalia should always be carried out at pre-discharge visit in hospital nurseries in order to exclude gross malformations, potentially compatible with genetic and/or ...

    • Hypothalamic AMPK-ER Stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance 

      Martinez-Sanchez, Noelia; Seoane-Collazo, Patricia; Contreras, Cristina; Varela, Luis; Villarroya, Joan; Rial-Pensado, Eva; Buque, Xabier; Aurrekoetxea, Igor; Delgado, Teresa C.; Vazquez-Martinez, Rafael; Gonzalez-Garcia, Ismael; Roa, Juan; Whittle, Andrew J.; Gomez-Santos, Beatriz; Velagapudi, Vidya; Loraine Tung, Y. C.; Morgan, Donald A.; Voshol, Peter J.; Martinez de Morentin, Pablo B.; Lopez-Gonzalez, Tania; Linares-Pose, Laura; Gonzalez, Francisco; Chatterjee, Krishna; Sobrino, Tomas; Medina-Gomez, Gema; Davis, Roger J.; Casals i Farré, Núria; Oresic, Matej; Coll, Anthony P.; Vidal-Puig, Antonio; Mittag, Jens; Tena-Sempere, Manuel; Malagon, Maria M.; Dieguez, Carlos; Martinez-Chantar, Maria Luz; Aspichueta, Patricia; Rahmouni, Kamal; Nogueiras, Rubén; Sabio, Guadalupe; Villarroya, Francesc; Lopez, Miguel (Cell Metabolism, 2017-07)
      Thyroid hormones (THs) act in the brain to modulate energy balance. We show that central triiodothyronine (T3) regulates de novo lipogenesis in liver and lipid oxidation in brown adipose tissue (BAT) ...

    • Hypothalamic endocannabinoids in obesity: an old story with new challenges 

      Miralpeix Monclús, Cristina; Reguera, Ana Cristina; Fosch, Anna; Zagmutt, Sebastián; Casals i Farré, Núria; Cota, Daniela; Rodríguez-Rodríguez, Rosalía (Cellular and Molecular Life Sciences, 2021)
      The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and cellular mechanisms involved are the focus of intense research. A disrupted ...

    • Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice 

      Miralpeix Monclús, Cristina; Fosch, Anna; Casas, Josefina; Baena, Miguel; Herrero Rodríguez, Laura; Serra, Dolors; Rodríguez-Rodríguez, Rosalía; Casals i Farré, Núria (Journal of Lipid Research, 2019-07)
      The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain ...

    • Hypothalamic regulation of obesity 

      Rodríguez-Rodríguez, Rosalía; Miralpeix Monclús, Cristina (International Journal of Molecular Sciences, 2021)
      Obesity has now reached pandemic proportions and represents a major socioeconomic and health problem in our societies. Up to now, obesity has been considered a medical issue only in high-income countries, ...

    • Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition 

      Morillas, Montserrat; Gómez-Puertas, Paulino; Bentebibel, Assia; Sellés, Eva; Casals i Farré, Núria; Valencia, Alfonso; Hegardt, Fausto G.; Asins, Guillermina; Serra, Dolors (Journal of Biological Chemistry, 2003-03-14)
      Carnitine palmitoyltransferase (CPT) I, which catalyzes the conversion of palmitoyl-CoA to palmitoylcarnitine facilitating its transport through the mitochondrial membranes, is inhibited by malonyl-CoA. ...

    • Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays 

      Sanchez, Mayka; Galy, Bruno; Hentze, Matthias W.; Muckenthaler, Martina U. (Nature Protocols, 2007)
      RNA-binding proteins (RBPs) frequently regulate the post-transcriptional fate of target mRNAs. To identify novel target mRNAs of RBPs, we incubate total RNA with recombinant RBP and immunoselect the ...

    • Identification of the ghrelin and cannabinoid CB2 receptor heteromer functionality and marked upregulation in striatal neurons from offspring of mice under a high-fat diet 

      Lillo, Jaume; Lillo, Alejandro; Zafra, David A.; Miralpeix Monclús, Cristina; Rivas-Santisteban, Rafael; Casals i Farré, Núria; Navarro, Gemma; Franco, Rafael (International Journal of Molecular Sciences, 2021)
      Cannabinoids have been reported as orexigenic, i.e., as promoting food intake that, among others, is controlled by the so-called “hunger” hormone, ghrelin. The aim of this paper was to look for functional ...