Now showing items 162-181 of 723

    • Current and future perspectives in lung cancer prevention 

      González-Marrón, Adrián; Martín-Sánchez, Juan Carlos; Martínez-Sánchez, Jose M. (Precision Cancer Medicine, 2020)
      Smoking is one of the leading causes of morbidity and mortality worldwide. Tobacco smoke contains thousands of different heterogeneous substances, dozens of them classified as carcinogenic for humans, ...
    • Current and future perspectives in lung cancer prevention 

      González-Marrón, Adrián; Martín-Sánchez, Juan Carlos; Martínez-Sánchez, Jose M. (Precision Cancer Medicine: a Journal Aiming to Deliver a Lasting Blow to Cancer, 2020)
      Smoking is one of the leading causes of morbidity and mortality worldwide. Tobacco smoke contains thousands of different heterogeneous substances, dozens of them classified as carcinogenic for humans, ...
    • Current challenges for targeting brown fat thermogenesis to combat obesity 

      Yoneshiro, Takeshi; Rodríguez-Rodríguez, Rosalía; Johannes Betz, Matthias; Rensen, Patrick C. N. (Frontiers in Endocrinology, 2020-10-27)
      Just over a decade has passed since metabolically active brown adipose tissue (BAT) was unequivocally identified in healthy adult humans. Since then, researchers have provided evidence of expression of ...
    • Current controversies in trichology: a European expert consensus statement 

      Meyer-Gonzalez, T.; Bacqueville, D.; Grimalt Santacana, Ramon; Mengeaud, V.; Piraccini, Bianca Maria; Rudnicka, L.; Saceda-Corralo, D.; Vogt, A.; Trichology Experts Network Group; Vano-Galvan, S. (Journal of the European Academy of Dermatology and Venereology, 2021)
      Introduction: Hair disorders are one of the most common conditions within dermatology practice but, although new diagnostic tools and therapeutic options have arisen, the management of these patients ...
    • Cystic fibrosis in Brazil: achievements in survival 

      Vendrusculo, Fernanda Maria; Fagundes Donadio, Márcio Vinícius; Araújo Pinto, Leonardo (Jornal Brasileiro de Pneumologia, 2021)
    • Daptomycin plus fosfomycin versus daptomycin alone for methicillin-resistant staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial 

      Pujol, Miquel; Miró, José-María; Shaw, Evelyn; Aguado, Jose-María; San-Juan, Rafael; Puig-Asensio, Mireia; Pigrau, Carles; Calbo Sebastián, Esther; Montejo, Miguel; Rodriguez-Álvarez, Regino; Garcia-Pais, María-Jose; Pintado, Vicente; Escudero-Sánchez, Rosa; Lopez-Contreras, Joaquín (Clinical Infectious Diseases, 2021)
      Background: We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and ...
    • Daptomycin plus fosfomycin versus daptomycin alone for methicillin-resistant staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial 

      Pujol, Miquel; Miró, José-María; Shaw, Evelyn; Aguado, Jose-María; San-Juan, Rafael; Puig-Asensio, Mireia; Pigrau, Carles; Calbo Sebastián, Esther; Montejo, Miguel; Rodriguez-Álvarez, Regino; Garcia-Pais, María-Jose; Pintado, Vicente; Escudero-Sánchez, Rosa; Lopez-Contreras, Joaquín; Morata, Laura; Montero, Milagros; Andrés, Marta; Pasquau, Juan; Arenas, María-del-Mar; Padilla, Belén; Murillas, Javier; Jover-Sáenz, Alfredo; López-Cortes, Luis-Eduardo; García-Pardo, Graciano; Gasch, Oriol; Videla, Sebastian; Hereu, Pilar; Tebé, Cristian; Pallarès, Natalia; Sanllorente, Mireia; Domínguez, María-Ángeles; Càmara, Jordi; Ferrer, Anna; Padullés, Ariadna; Cuervo, Guillermo; Carratalà, Jordi; MRSA Bacteremia (BACSARM) Trial Investigators (Clinical Infectious Diseases, 2020)
      Background: We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and ...
    • Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1 

      Hernández, Gonzalo; Ramírez, María José; Minguillón, Jordi; Quiles, Paco; Ruiz de Garibay, Gorka; Aza-Carmona, Miriam; Bogliolo, Massimo; Pujol, Roser; Prados-Carvajal, Rosario; Fernández, Juana; García, Nadia; López, Adrià; Gutiérrez-Enríquez, Sara; Diez, Orland; Benítez, Javier; Salinas, Mónica; Teulé, Alex; Brunet, Joan; Radice, Paolo; Peterlongo, Paolo; Schindler, Detlev; Huertas, Pablo; Puente, Xose S.; Lázaro, Conxi; Pujana, Miquel Àngel; Surrallés, Jordi (Nature Communications, 2018)
      BRCA1 is a tumor suppressor that regulates DNA repair by homologous recombination. Germline mutations in BRCA1 are associated with increased risk of breast and ovarian cancer and BRCA1 deficient tumors ...
    • Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation 

      Hernández-Ortega, Sara; Bru Rullo, Samuel; Ricco Pacheco, Natalia; Ramírez, Sara; Casals i Farré, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet Erra, Josep (Journal of Biological Chemistry, 2013-02)
      Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ...
    • Definition and validation of the nursing diagnosis label “wish to die”: a research protocol 

      Monforte-Royo, Cristina; Goni-Fuste, Blanca; Crespo, Iris; Pergolizzi, Denise; Martin Delgado, Leandra; Fuster, Pilar; Bellido Perez, Mercedes; Tomás Sábado, Joaquín; Rodríguez Prat, Andrea (BMC Nursing, 2024)
      Background: Euthanasia has been incorporated into the health services of seven countries. The legalisation of these practices has important repercussions for the competences of nurses, and it raises ...
    • Deformations and ruptures in human lenses with cortical cataract subjected to ex vivo simulated accommodation 

      Michael, Ralph; D'Antin, Justin Christopher; Pinilla Cortés, Laura; Burd, Harvey John; Sheil, Brian; Barraquer, Rafael I. (Investigative Ophthalmology & Visual Science, 2021)
      Purpose: Human cortical opacities are most commonly accompanied by changes in lens fiber structure in the equatorial region at the lens nucleus–cortex interface. Cortex and nucleus have different elastic ...
    • Delayed cerebral vasculopathy in pneumococcal meningitis: epidemiology and clinical outcome. A cohort study 

      Boix-Palop, Lucía; Fernández, Tamara; Pelegrín, Iván; Obradors, Meritxell; García-Roulston, Kevin; Xercavins Valls, Mariona; García-Somoza, Dolors; Ardanuy, Carmen; Grau, Javier; Calbo Sebastián, Esther; Cabellos, Carmen (International Journal of Infectious Diseases, 2020-08)
      Background: To describe the prevalence, clinical characteristics, impact of systemic steroids exposure and outcomes of delayed cerebral vasculopathy (DCV) in a cohort of adult patients with pneumococcal ...
    • Demanda de autonomía en la relación entre los adolescentes y sus padres 

      Alonso Stuyck, Paloma; Aliaga, Francisco M. (Estudios sobre Educación, 2017)
      In a family setting, disagreements between parents and their teenage children are commonplace. This study seeks to measure a teenager's degree of independence alongside their level of communication with ...
    • The dermoscopic “chromosome arms sign” for terra firma-forme dermatosis 

      Cutrone, Mario; Van Gysel, Julie; Grimalt Santacana, Ramon (Openventio, 2021)
      Introduction: Terra firma-forme dermatosis (TFFD) belongs to the group of “dirty dermatoses” and represents a not well-known and surely underestimated skin condition. Clinical cases: We present 2 cases ...
    • Desarrollo de materiales educativos para pacientes crónicos y familiares 

      Navarro Rubio, María Dolors; Gálvez Hernández, Pablo; González de Paz, Lluís; Virumbrales Cancio, Montserrat; Borrás Santos, Alicia; Santesmases Masana, Rosalia; Real Gatius, Jordi; Amo, Isabel; Macías, Felipe (Educación Médica, 2019)
      Un nivel bajo de alfabetización puede dificultar la comprensión de la información necesaria para tomar decisiones apropiadas en relación con la propia salud. Esta situación está relacionada con una peor ...
    • Descriptive analysis of cystic fibrosis patients followed by the Pediatric Pulmonology Unit of a university hospital in Porto Alegre-RS 

      Gava Chakr, Valentina C. B.; Vendrusculo, Fernanda Maria; Tomedi Leites, Gabriela; Fagundes Donadio, Márcio Vinícius; Frescura Paim, Taísa; Cauduro Marostica, Paulo José; Rúbia Silveira, Mara (Scientia Medica, 2006)
      Aims: To provide a descriptive analysis of patients followed in a local cystic fibrosis treatment center and compare the collected data with those found in the literature. Methods: Relevant data for ...
    • Detection and expression analysis of tet(B) in streptococcus oralis 

      Arredondo, Alexandre; Àlvarez, Gerard; Nart Molina, José; Mor Reinoso, Carolina; Blanc, Vanessa; León, Rubén (Journal of Oral Microbiology, 2019)
      Tetracycline resistance can be achieved through tet genes, which code for efflux pumps, ribosomal protection proteins and inactivation enzymes. Some of these genes have only been described in either ...
    • Determinants of depressive symptoms in people living with HIV: findings from a population-based study with a gender perspective 

      Bayés Marín, Ivet; Egea Cortés, Laia; Palacio Vieira, Jorge; Bruguera Riera, Andreu; Mesías Gazmuri, Jocelyn; Llibre, Josep M; Fernández, Emma; Imaz, Arkaitz; G. Forero, Carlos; Agustí, Cristina; Arbones, Laia; Miro, Jose M; Casabona, Jordi; Reyes Ureña, Juliana (International Journal of Environmental Research and Public Health, 2023)
      Depressive symptoms are common among people living with HIV (PLWH). The aim of this study was to identify the determinants of depressive symptoms in PLWH in Spain. A total of 1060 PLWH participated in ...
    • Determinants of study completion and response to a 12-month behavioral physical activity intervention in chronic obstructive pulmonary disease: a cohort study 

      Koreny, Maria; Demeyer, Heleen; Arbillaga-Etxarri, Ane; Gimeno-Santos, Elena; Barberan-Garcia, Anael; Benages Albert, Marta; Balcells, Eva; Borrell, Eulàlia; Marín, Alicia; Rodríguez Chiaradía, Diego A.; Vall Casas, Pere; Vilaró, Jordi; Rodríguez-Roisin, Robert; Garcia-Aymerich, Judith (PLoS ONE, 2019-05-20)
      Objectives: Physical activity is key to improve the prognosis of chronic obstructive pulmonary disease (COPD). To help to tailor future interventions we aimed to identify the baseline characteristics ...
    • Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth 

      Martin Gili, David; Molmeneu Trias, Meritxell; Fernández Yagüe, Marc Antoni; Punset Fuste, Miquel; Giner Tarrida, Lluís; Armengou, Jaume; Gil Mur, Francisco Javier (Journal of Materials Science: Materials in Medicine, 2015-07-15)
      This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical ...