Browsing Ciències de la Salut by Title
Now showing items 77-96 of 723
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Biofabrication of collagen tissue-engineered blood vessels with direct co-axial extrusion
(International Journal of Molecular Sciences, 2022)Cardiovascular diseases are considered one of the worldwide causes of death, with atherosclerosis being the most predominant. Nowadays, the gold standard treatment is blood vessel replacement by bypass ... -
Biofabrication of tissue engineering vascular systems
(APL Bioengineering, 2021-05)Cardiovascular disease (CVD) is the leading cause of death among persons aged 65 and older in the United States and many other developed countries. Tissue engineered vascular systems (TEVS) can serve ... -
Biofunctionalization strategies on tantalum-based materials for osseointegrative applications
(Journal of Materials Science: Materials in Medicine, 2015)The use of tantalum as biomaterial for orthopedic applications is gaining considerable attention in the clinical practice because it presents an excellent chemical stability, body fluid resistance, ... -
Biofunctionalization with a TGFβ-1 inhibitor peptide in the osseointegration of synthetic bone grafts: an in vivo study in beagle dogs
(Materials, 2019-09-27)Objectives: The aim of this research was to determine the osseointegration of two presentations of biphasic calcium phosphate (BCP) biomaterial—one untreated and another submitted to biofunctionalization ... -
Biological roles and delivery strategies for ions to promote osteogenic induction
(Frontiers in Cell and Developmental Biology, 2021-01-14)Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ... -
Biomedical doctoral students’ research practices when facing dilemmas: two vignette-based randomized control trials
(Scientific Reports, 2023)Our aim was to describe the research practices of doctoral students facing a dilemma to research integrity and to assess the impact of inappropriate research environments, i.e. exposure to (a) a ... -
Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle
(Journal of Biological Chemistry, 1994-04-22)The isoprenoid pathway leads to various essential non-sterol products in insects. These end products have a crucial role in growth, differentiation, sexual maturation, and reproduction. 3-Hydroxy-3-me ... -
Blood test dynamics in hospitalized COVID-19 patients: Potential utility of D-dimer for pulmonary embolism diagnosis
(PLoS One, 2020-12-28)Background: A higher incidence of thrombotic events, mainly pulmonary embolism (PE), has been reported in hospitalized patients with COVID-19. The main objective was to assess clinical and laboratory ... -
Boceprevir plus pegylated interferon/ribavirin to re-treat hepatitis C virus genotype 1 in HIV–HCV co-infected patients: final results of the Spanish BOC HIV–HCV Study
(International Journal of Infectious Diseases, 2016-12)Introduction: Boceprevir (BOC) was one of the first oral inhibitors of hepatitis C virus (HCV) NS3 protease to be developed. This study assessed the safety and efficacy of BOC + pegylated interferon-α ... -
Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis
(Jornal de Pediatria, 2013)Objective: To assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables. Methods: Children and adolescents diagnosed with CF, aged 6 to ... -
Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway
(2009-12-15)Bone morphogenetic proteins (BMPs) have been implicated in the generation and postnatal differentiation of cerebellar granule cells (CGCs). Here, we examined the eventual role of BMPs on the survival ... -
Breast cancer-related lymphoedema: risk factors and prediction model
(Journal of Advanced Nursing, 2021)Aims: To identify the risk factors for lymphoedema following axillary lymph node dissection (ALND) in a European sample and to propose a lymphoedema prediction model for this population. Design: Predictive ... -
Bullous henoch-schönlein purpura: a case series
(Journal of Respiratory Research, 2019-12)Henoch-Schönlein purpura (HSP) represents the most common vasculitis in children. Typically, HSP manifests with palpable purpura and edema, usually following an urticarial or erythematous maculopapular ... -
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Preventive Medicine, 2019-12)Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ... -
Caracterización del microbioma nasofaríngeo en pacientes con enfermedad de Kawasaki
(2022)Introducción: La etiología de la enfermedad de Kawasaki (EK) sigue siendo desconocida. Varios estudios han relacionado el microbioma humano con algunas enfermedades. Sin embargo, los estudios sobre el ... -
Cardiopulmonary coupling indices to assess weaning readiness from mechanical ventilation
(Scientific Reports, 2021)The ideal moment to withdraw respiratory supply of patients under Mechanical Ventilation at Intensive Care Units (ICU), is not easy to be determined for clinicians. Although the Spontaneous Breathing ... -
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
(British Journal of Pharmacology, 2021-01)Background and Purpose: The enzyme α/β‐hydrolase domain containing 6 (ABHD6), a new member of the endocannabinoid system, is a promising therapeutic target against neuronal‐related diseases. However, ... -
Catheter-directed therapies in patients with pulmonary embolism: predictive factors of in-hospital mortality and long-term follow-up
(Journal of Clinical Medicine, 2021)Background: Catheter-directed therapies (CDT) may be considered for selected patients with pulmonary embolism (PE); (2) Methods: Retrospective observational study including all consecutive patients with ... -
CDK-mediated Yku80 phosphorylation regulates the balance between non-homologous end joining (NHEJ) and homologous directed recombination (HDR)
(Journal of Molecular Biology, 2020)There are two major pathways for repairing DNA double-strand breaks (DSBs): homologous directed recombination (HDR) and non-homologous end-joining (NHEJ). While NHEJ functions throughout the cell cycle, ... -
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
(Molecular Oncology, 2023)Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...