Browsing Ciències de la Salut by Title

Now showing items 68-87 of 723

    • Atypical cyclin P regulates cancer cell stemness through activation of the WNT pathway 

      Sánchez‑Botet, Abril; Quandt Herrera, Eva; Masip, Núria; Escribá, Rubén; Novellasdemunt, Laura; Gasa Colom, Laura; Li, Vivian S. W.; Raya, Ángel; Clotet Erra, Josep; Ribeiro, Mariana P. C. (Cellular Oncology, 2021)
      Purpose: Cancer stem cells represent a cancer cell subpopulation that has been found to be associated with metastasis and chemoresistance. Therefore, it is vital to identify mechanisms regulating cancer ...

    • Atypical cyclins: the extended family portrait 

      Quandt Herrera, Eva; Ribeiro, Mariana P. C.; Clotet Erra, Josep (Cellular and Molecular Life Sciences, 2020)
      Regulation of cell division is orchestrated by cyclins, which bind and activate their catalytic workmates, the cyclin-dependent kinases (CDKs). Cyclins have been traditionally defined by an oscillating ...

    • Automatic detection of ventilatory modes during invasive mechanical ventilation 

      Murias, Gastón; Montanyà, Jaume; Chacón, Encarna; Estruga, Anna; Subirà Cuyàs, Carles; Fernández Fernández, Rafael; Sales, Bernat; De Haro, Candelaria; López-Aguilar, Josefina; Lucangelo, Umberto; Villar, Jesús; Kacmarek, Robert M.; Blanch, Lluís (Critical Care, 2016-08-14)
      Background: Expert systems can help alleviate problems related to the shortage of human resources in critical care, offering expert advice in complex situations. Expert systems use contextual information ...

    • Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning 

      Gómez-Valverde, Juan J.; Antón López, Alfonso; Fatti, Gianluca; Liefers, Bart; Herranz, Alejandra; Santos, Andrés; Sánchez, Clara I.; Ledesma-Carbayo, María J. (Biomedical Optics Express, 2019-02-01)
      Glaucoma detection in color fundus images is a challenging task that requires expertise and years of practice. In this study we exploited the application of different Convolutional Neural Networks (CNN) ...

    • Automatic SCOring of atopic dermatitis using deep learning (ASCORAD): a pilot study 

      Medela, Alfonso; Mac Carthy, Taig; Aguilar Robles, S. Andy; Chiesa-Estomba, Carlos M.; Grimalt Santacana, Ramon (JID Innovations, 2022)
      Atopic dermatitis (AD) is a chronic, itchy skin condition that affects 15–20% of children, but may occur at any age. It is estimated that 16.5 million U.S. adults (7.3%) have AD that initially began at ...

    • Basic life support and external defibrillation competences after instruction and at 6 months comparing face-to-face and blended training. Randomised trial 

      Castillo, Jordi; Gallart Fernández-Puebla, Alberto; Rodríguez, Encarnación; Castillo, Jorge; Gomar, Carmen (Nurse Education Today, 2018)
      Aim of the Study: The objective of this study was to compare the immediate and 6-month efficacy of basic life support (BLS) and automatic external defibrillation (AED) training using standard or blended ...

    • Beneficial effect of corticosteroids in preventing mortality in patients receiving tocilizumab to treat severe COVID-19 illness 

      Rubio-Rivas, Manuel; Ronda, Mar; Padullés, Ariadna; Mitjavila, Francesca; Riera-Mestre, Antoni; García-Forero, Carlos; Iriarte, Adriana; Mora-Luján, José María; Padullés, Núria; Gonzalez, Monica; Solanich, Xavier; Gasa, Merce; Suarez-Cuartin, Guillermo; Sabater-Riera, Joan; Perez-Fernandez, Xose L.; Santacana, Eugenia; Leiva, Elisabet; Ariza-Sole, Albert; Dallaglio, Paolo D.; Quero, Maria; Soriano, Antonio; Pasqualetto, Alberto; Koo, Maylin; Esteve-Luque, Virginia; Antolí, Arnau; Moreno-Gónzalez, Rafael; Yun, Sergi; Cerdà, Pau; Llaberia, Mariona; Formiga, Francesc; Fanlo-Maresma, Marta; Montero, Abelardo; Chivite, David; Capdevila, Olga; Bolao, Ferran; Pintó, Xavier; Llop, Josep; Sabate, Antoni; Guardiola, Jordi; Cruzado, Josep M.; Comin-Colet, Josep; Santos, Salud; Jodar, Ramon; Corbella Virós, Xavier (Elsevier, 2020-12)
      Objectives: To assess the characteristics and risk factors for mortality in patients with severe coronavirus disease-2019 (COVID-19) treated with tocilizumab (TCZ), alone or in combination with ...

    • A beta version of an application based on computer vision for the assessment of knee valgus angle: a validity and reliability study 

      Ceballos Laita, Luis; Marimon Serra, Xavier; Masip-Alvarez, Albert; Cabanillas-Barea, Sara; Jiménez, Sandra; Carrasco-Uribarren, Andoni (Healthcare, 2023)
      Background: In handball, the kinematics of the frontal plane seem to be one of the most important factors for the development of lower limb injuries. The knee valgus angle is a fundamental axis for ...

    • Biceps femoris activation during hamstring strength exercises: a systematic review 

      Llurda-Almuzara, Luis; Labata-Lezaun, Noé; López de Celis, Carlos; Aiguadé Aiguadé, Ramón; Romaní-Sánchez, Sergi; Rodríguez-Sanz, Jacobo; Fernández-de-las-Peñas, César; Pérez Bellmunt, Albert (International Journal of Environmental Research and Public Health, 2021)
      Background: The aim of the study was to systematically evaluate the biceps femoris long head activation across cross-sectional hamstring strength exercise studies. Methods: A systematic review design ...

    • Biofabrication of collagen tissue-engineered blood vessels with direct co-axial extrusion 

      Bosch Rué, Elia; Díez-Tercero, Leire; Delgado, Luis Maria; Perez, Roman (International Journal of Molecular Sciences, 2022)
      Cardiovascular diseases are considered one of the worldwide causes of death, with atherosclerosis being the most predominant. Nowadays, the gold standard treatment is blood vessel replacement by bypass ...

    • Biofabrication of tissue engineering vascular systems 

      Zhang, Qiao; Bosch-Rué, Elia; Pérez Antoñanzas, Roman; Truskey, George A. (APL Bioengineering, 2021-05)
      Cardiovascular disease (CVD) is the leading cause of death among persons aged 65 and older in the United States and many other developed countries. Tissue engineered vascular systems (TEVS) can serve ...

    • Biofunctionalization strategies on tantalum-based materials for osseointegrative applications 

      Mas Moruno, Carlos; Garrido, Beatriz; Rodriguez, Daniel; Rupérez de Gracia, Elisa; Gil Mur, Francisco Javier (Journal of Materials Science: Materials in Medicine, 2015)
      The use of tantalum as biomaterial for orthopedic applications is gaining considerable attention in the clinical practice because it presents an excellent chemical stability, body fluid resistance, ...

    • Biofunctionalization with a TGFβ-1 inhibitor peptide in the osseointegration of synthetic bone grafts: an in vivo study in beagle dogs 

      Cirera, Andrea; Manzanares-Céspedes, Maria Cristina; Sevilla Sánchez, Pablo; Ortiz-Hernández, Monica; Galindo-Moreno, Pablo; Gil Mur, Francisco Javier (Materials, 2019-09-27)
      Objectives: The aim of this research was to determine the osseointegration of two presentations of biphasic calcium phosphate (BCP) biomaterial—one untreated and another submitted to biofunctionalization ...

    • Biological roles and delivery strategies for ions to promote osteogenic induction 

      Bosch-Rué, Elia; Diez-Tercero, Leire; Giordano-Kelhoffer, Barbara; Delgado, Luis M.; Bosch Canals, Begoña María; Hoyos Nogués, Mireia; Mateos-Timoneda, Miguel Angel; Tran, Phong A.; Gil Mur, Francisco Javier; Pérez Antoñanzas, Roman (Frontiers in Cell and Developmental Biology, 2021-01-14)
      Bone is the most studied tissue in the field of tissue regeneration. Even though it has intrinsic capability to regenerate upon injury, several pathologies and injuries could hamper the highly orchestrated ...

    • Biomedical doctoral students’ research practices when facing dilemmas: two vignette-based randomized control trials 

      Nguyen, V.T.; Sharp, M. K.; Superchi, C.; Baron, G.; Glonti, K.; Blanco de Tena Davila, David; Olsen, M.; Tat, T.T Vo; Olarte Parra, C.; Névéol, A.; Hren, D.; Ravaud, P.; Boutron, I. (Scientific Reports, 2023)
      Our aim was to describe the research practices of doctoral students facing a dilemma to research integrity and to assess the impact of inappropriate research environments, i.e. exposure to (a) a ...

    • Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle 

      Buesa, Carlos; Martínez-Gonzalez, José; Casals i Farré, Núria; Haro, Diego; Piulachs, Maria-Dolors; Bellés, Xavier; Hegardt, Fausto G. (Journal of Biological Chemistry, 1994-04-22)
      The isoprenoid pathway leads to various essential non-sterol products in insects. These end products have a crucial role in growth, differentiation, sexual maturation, and reproduction. 3-Hydroxy-3-me ...

    • Blood test dynamics in hospitalized COVID-19 patients: Potential utility of D-dimer for pulmonary embolism diagnosis 

      Cerdà, Pau; Ribas, Jesús; Iriarte, Adriana; Mora-Luján, José María; Torres, Raquel; Del Río, Belén; Jofre, Héctor Ignacio; Ruiz, Yolanda; Huguet, Marta; Fuset, Mari Paz; Martínez-Yélamos, Sergio; Santos, Salud; Llecha, Núria; Corbella Virós, Xavier; Riera-Mestre, Antoni (PLoS One, 2020-12-28)
      Background: A higher incidence of thrombotic events, mainly pulmonary embolism (PE), has been reported in hospitalized patients with COVID-19. The main objective was to assess clinical and laboratory ...

    • Boceprevir plus pegylated interferon/ribavirin to re-treat hepatitis C virus genotype 1 in HIV–HCV co-infected patients: final results of the Spanish BOC HIV–HCV Study 

      Laguno, M.; Von Wichmann, M. A.; Van den Eynde, E.; Navarro, J.; Cifuentes, Carmen; Murillas, J.; Veloso, S.; Martínez-Rebollar, M.; Guardiola, J.M.; Jou, A.; Gómez-Sirvent, J.L.; Cervantes, M.; Pineda, J.A.; López-Calvo, S.; Carrero, Ana; Montes, M.L.; Deig, E.; Tapiz, A.; Ruiz-Mesa, J.D.; Cruceta, A.; de Lazzari, E.; Mallolas, Josep (International Journal of Infectious Diseases, 2016-12)
      Introduction: Boceprevir (BOC) was one of the first oral inhibitors of hepatitis C virus (HCV) NS3 protease to be developed. This study assessed the safety and efficacy of BOC + pegylated interferon-α ...

    • Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis 

      Donadio, Márcio V.F.; De Souza, Guilherme C.; Tiecher, Gabriele; Heinzmann-Filho, João P.; Paim, Taísa F.; Hommerding, Patrícia X.; Marosticaf, Paulo J.C. (Jornal de Pediatria, 2013)
      Objective: To assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables. Methods: Children and adolescents diagnosed with CF, aged 6 to ...

    • Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathway 

      Barneda-Zahonero, Bruna; Miñano Molina, Alfredo Jesús; Badiola, Nahuai; Fadó Andrés, Rut; Xifró Collsamata, Xavier; Saura, Carlos A.; Rodríguez Álvarez, José (2009-12-15)
      Bone morphogenetic proteins (BMPs) have been implicated in the generation and postnatal differentiation of cerebellar granule cells (CGCs). Here, we examined the eventual role of BMPs on the survival ...