Browsing Ciències de la Salut by Subject "616.2"

Now showing items 21-25 of 25

    • A social return on investment analysis of improving the management of chronic obstructive pulmonary disease within the spanish national healthcare system 

      Merino, María; Martín Lorenzo, Teresa; Maravilla-Herrera, P.; Ancochea, julio; Gómez Sáenz, JT; Hass, Nicole; MOLINA, JESUS; Peces-Barba, G.; Trapero-Bertran, Marta; trigueros, juan antonio; Hidalgo, Alvaro (International Journal of Chronic Obstructive Pulmonary Disease, 2022)
      Purpose: To define a set of proposals that would improve the current management of chronic obstructive pulmonary disease (COPD) within the Spanish National Healthcare System (SNHS) from a comprehensive ...

    • A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer 

      Gasa Colom, Laura; Sánchez Botet, Abril; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Carrasco García, Miguel Ángel; Simonetti, Sara; Kron, Stephen J.; P.C. Ribeiro, Mariana; Nadal, E; Villanueva, Alberto; Clotet Erra, Josep (2017-08-31)
      As lung cancer has increased to the most common cause of cancer death worldwide, prognostic biomarkers and efective targeted treatments remain lacking despite advances based on patients’ stratifcation. ...

    • Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells 

      Page, Brent D.G.; Valerie, Nicholas C.K.; Wright, Roni H.G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlöf, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundbäck, Thomas; Scobie, Martin; Strömberg, Kia; Stenmark, Pål; Beato, Miguel; Helleday, Thomas (Nature Communications, 2018)
      With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...

    • Urban environment and physical activity and capacity in patients with chronic obstructive pulmonary disease 

      Koreny, Maria; Arbillaga-Etxarri, Ane; Bosch de Basea, Magda; Foraster, Maria; Carsin, Anne-Elie; Cirach, Marta; Gimeno-Santos, Elena; Barberan-Garcia, Anael; Nieuwenhuijsen, Mark; Vall-Casas, Pere; Rodriguez-Roisín, Robert; Garcia-Aymerich, Judith (Environmental Research, 2022)
      Background: Physical activity and exercise capacity are key prognostic factors in chronic obstructive pulmonary disease (COPD) but their environmental determinants are unknown. Objectives: To test the ...

    • Variation in nicotine metabolization according to biological factors and type of nicotine consumer 

      Pérez-Martín, Hipólito; Lidón-Moyano, Cristina; González-Marrón, Adrián; Fu, Marcela; Pérez Ortuño, Raúl; Ballbè, Montse; Martín-Sánchez, Juan Carlos; Pascual, José A.; Fernández, Esteve; Martínez-Sánchez, Jose M. (Healthcare, 2023)
      This study aims to describe the nicotine metabolite ratio among tobacco smokers and electronic cigarette (e-cigarette) users and nonusers. We analyzed pooled data from a longitudinal and a cross-sectional ...