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dc.contributor.authorMoreno Montañés, Javier
dc.contributor.authorGarcía Nieva, Ana
dc.contributor.authorAristeguieta Osio, Indira
dc.contributor.authorGuarnieri, Adriano
dc.contributor.authorMorilla Grasa, Antonio
dc.contributor.authorGarcía Granero, Marta
dc.contributor.authorAntón López, Alfonso
dc.identifier.citationMoreno Montañés, Javier; García Nieva, Ana; Aristeguieta Osio, Indira; Guarnieri, Adriano; Morilla Grasa, Antonio; García Granero, Marta; Antón López, Alfonso. «Evaluation of RETICs glaucoma diagnostic calculators in preperimetric glaucoma». Translational Vision Science & Technology, 2018, vol. 7, núm. 6, art. 13. Disponible en: <>. Fecha de acceso: 26 sept. 2019. DOI:
dc.description.abstractPurpose: To evaluate two glaucoma diagnostic calculators (GDC) in a group of eyes with preperimetric glaucoma (PPG). Methods: All eyes (n = 265) included in this study had ocular hypertension with normal visual fields (VFs) on repeated VF tests. PPG was defined as progression in the Guided Progression Analysis software from Cirrus-optical coherence tomography (GPA-OCT). Three PPG types were defined according to the GPA-OCT software as follows: (1) GPA-OCT with one or more red boxes in two or more columns; (2) GPA-OCT with two or more red boxes in two or more columns; and (3) GPA-OCT with two or more red boxes in two or more columns (definition 2), and in the last scan one or more red box in the RNFL average or quadrants. Nonparametric tests, areas under the receiver operating characteristic curve (AUC), and Bland-Altman tests were assessed. Results: Definitions one, two, and three were met by 44 (16.6%), 29 (10.9%), and 11 (4.2%) eyes, respectively. The GDC indices (means ± standard deviations) were, respectively, 14.49 ± 21.55% and 26.06 ± 22.50% using the combined and quantitative GDC (P < 0.001) in all eyes. Both GDC showed higher glaucoma probability in the PPG group (P < 0.04; combined GDC AUCs, 0.720–0.833; quantitative GDC AUCs, 0.700–0.839). GDC values were higher (P < 0.01) with greater GPA progression. Conclusions: The values of both GDC were higher in the PPG group than the ocular hypertension group. The GDC were higher when more columns in the GPA software indicated progression. Both GDC showed a similar ability to detect PPG. Translational Relevance: These calculators facilitate diagnosis of PPG in ocular hypertensive
dc.publisherAssociation for Research in Vision and Ophthalmologyca
dc.relation.ispartofTranslational Vision Science & Technologyca
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.titleEvaluation of RETICs glaucoma diagnostic calculators in preperimetric glaucomaca

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