dc.contributor.author | Hoyos Nogués, Mireia | |
dc.contributor.author | Gil Mur, Francisco Javier | |
dc.contributor.author | Mas Moruno, Carlos | |
dc.date.accessioned | 2019-09-20T09:49:21Z | |
dc.date.available | 2019-09-20T09:49:21Z | |
dc.date.issued | 2018-07-10 | |
dc.identifier.citation | Hoyos Nogués, Mireia; Gil Mur, Francesc Xavier; Mas Moruno, Carlos. «Antimicrobial peptides: powerful biorecognition elements to detect bacteria in biosensing technologies». Molecules, 2018, vol. 23, núm. 7, 1683. Disponible en: <https://www.mdpi.com/1420-3049/23/7/1683>. Fecha de acceso: 20 sept. 2019. https://doi.org/10.3390/molecules23071683 | ca |
dc.identifier.issn | 1420-3049 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/1237 | |
dc.description | This article belongs to the Special Issue Antimicrobial Peptides and Peptidomimetics | ca |
dc.description.abstract | Bacterial infections represent a serious threat in modern medicine. In particular, biofilm
treatment in clinical settings is challenging, as biofilms are very resistant to conventional antibiotic
therapy and may spread infecting other tissues. To address this problem, biosensing technologies are
emerging as a powerful solution to detect and identify bacterial pathogens at the very early stages of
the infection, thus allowing rapid and effective treatments before biofilms are formed. Biosensors
typically consist of two main parts, a biorecognition moiety that interacts with the target (i.e., bacteria)
and a platform that transduces such interaction into a measurable signal. This review will focus on
the development of impedimetric biosensors using antimicrobial peptides (AMPs) as biorecognition
elements. AMPs belong to the innate immune system of living organisms and are very effective in
interacting with bacterial membranes. They offer unique advantages compared to other classical
bioreceptor molecules such as enzymes or antibodies. Moreover, impedance-based sensors allow the
development of label-free, rapid, sensitive, specific and cost-effective sensing platforms. In summary,
AMPs and impedimetric transducers combine excellent properties to produce robust biosensors for
the early detection of bacterial infections. | ca |
dc.format.extent | 24 | ca |
dc.language.iso | eng | ca |
dc.publisher | MDPI | ca |
dc.relation.ispartof | Molecules | ca |
dc.relation.ispartofseries | 23;7 | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/4.0/ | ca |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject.other | Bacteris | ca |
dc.subject.other | Bacteria | ca |
dc.subject.other | Bacterias | ca |
dc.subject.other | Biosensors | ca |
dc.subject.other | Biosensores | ca |
dc.subject.other | Espectroscòpia d'impedància | ca |
dc.subject.other | Impedance spectroscopy | ca |
dc.title | Antimicrobial peptides: powerful biorecognition elements to detect bacteria in biosensing technologies | ca |
dc.type | info:eu-repo/semantics/review | ca |
dc.description.version | info:eu-repo/semantics/acceptedVersion | ca |
dc.embargo.terms | cap | ca |
dc.subject.udc | 577 | ca |
dc.identifier.doi | https://doi.org/10.3390/molecules23071683 | ca |