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Antimicrobial GL13K peptide coatings killed and ruptured the wall of streptococcus gordonii and prevented formation and growth of biofilms
(Public Library of Science, 2014)
Infection is one of the most prevalent causes for dental implant failure. We have developed a novel antimicrobial peptide coating on titanium by immobilizing the antimicrobial peptide GL13K. GL13K was ...
PLA-based mineral-doped scaffolds seeded with human periapical cyst-derived MSCs: a promising tool for regenerative healing in dentistry
(MDPI, 2019)
Human periapical cyst mesenchymal stem cells (hPCy-MSCs) are a newly discovered cell population innovatively collected from inflammatory periapical cysts. The use of this biological waste guarantees a ...
Chitosan-recombinamer layer-by-layer coatings for multifunctional implants
(MDPI, 2017)
The main clinical problems for dental implants are (1) formation of biofilm around the implant—a condition known as peri-implantitis and (2) inadequate bone formation around the implant—lack of ...
Discerning the subfibrillar structure of mineralized collagen fibrils: a model for the ultrastructure of bone
(Public Library of Science, 2013)
Biomineralization templated by organic molecules to produce inorganic-organic nanocomposites is a fascinating example of nature using bottom-up strategies at nanoscale to accomplish highly ordered ...
Surface immobilization chemistry of a laminin-derived peptide affects keratinocyte activity
(MDPI, 2020)
Many chemical routes have been proposed to immobilize peptides on biomedical device surfaces, and in particular, on dental implants to prevent peri-implantitis. While a number of factors affect peptide ...
Targeting the oral plaque microbiome with immobilized anti-biofilm peptides at tooth-restoration interfaces
(Public Library of Science, 2020)
Recurrent caries, the development of carious lesions at the interface between the restorative material and the tooth structure, is highly prevalent and represents the primary cause for failure of dental ...