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Derivation of nearest-neighbor DNA parameters in magnesium from single molecule experiments
(Oxford University Press, 2017)
DNA hybridization is an essential molecular reaction in biology with many applications. The nearest-neighbor (NN) model for nucleic acids predicts DNA thermodynamics using energy values for the different ...
Single-molecule derivation of salt dependent base-pair free energies in DNA
(National Academy of Sciences, 2010)
Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in ...
Investigating the thermodynamics of small biosystems with optical tweezers
(Elsevier, 2010)
We present two examples of how single-molecule experimental techniques applied to biological systems can give insight into problems within the scope of equilibrium and nonequilibrium mesoscopic ...