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Automatic glaucoma classification using color fundus images based on convolutional neural networks and transfer learning
(Biomedical Optics Express, 2019-02-01)
Glaucoma detection in color fundus images is a challenging task that requires expertise and years of practice. In this study we exploited the application of different Convolutional Neural Networks (CNN) ...
Agreement among spectral-domain optical coherence tomography, standard automated perimetry, and stereophotography in the detection of glaucoma progression
(Investigative Ophthalmology & Visual Science, 2015-02)
PURPOSE. The purpose of this study was to evaluate the agreement among spectral-domain optical coherence tomography, standard automated perimetry (SAP), and optic disc stereo photography in the detection ...
Trichoscopy: essentials for the dermatologist
(World Journal of Dermatology, 2015-05-02)
Noninvasive in vivo imaging techniques have become an important diagnostic aid for dermatology. Dermoscopy, also known as dermatoscopy, has been shown to increase the clinician’s diagnostic accuracy ...
Reconfigurable multiplexed point of care system for monitoring type 1 diabetes patients
(Biosensors and Bioelectronics, 2019-07)
At the point of care (POC), on-side clinical testing allows fast biomarkers determination even in resource-limited environments. Current POC systems rely on tests selective to a single analyte or complex ...
The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
(Genome Biology, 2010-06-23)
Background: The G1-to-S transition of the cell cycle in the yeast Saccharomyces cerevisiae involves an extensive
transcriptional program driven by transcription factors SBF (Swi4-Swi6) and MBF (Mbp1-Swi6). ...
Short-term effect of antibiotics on human gut microbiota
(PLoS ONE, 2014-04-18)
From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an adult-like stage at three years of age. After this age, the composition may fluctuate in response to external ...
Economic modelling of diagnostic and treatment pathways in National Institute for Health and Care Excellence clinical guidelines: The Modelling Algorithm Pathways in Guidelines (MAPGuide) project
(Health Technology Assessment, 2013-12)
Background: National Institute for Health and Care Excellence (NICE) clinical guidelines (CGs) make recommendations across large, complex care pathways for broad groups of patients. They rely on ...
Why methylene blue should be blacklisted in neonatology
(Journal of Respiratory Research, 2019)
We here present a case of neonatal skin damage due to application of methylene blue (MB) on a newborn's skin. MB use should be completely eliminated in neonatal intensive care units and nurseries, because ...
Mechanisms of CPT1C-Dependent AMPAR trafficking enhancement
(Frontiers in Molecular Neuroscience, 2018-08-08)
In neurons, AMPA receptor (AMPAR) function depends essentially on their constituent
components: the ion channel forming subunits and ion channel associated proteins.
On the other hand, AMPAR trafficking ...
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
(Nature Communications, 2012-08-21)
Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size ...