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Regulation of actin dynamics during structural plasticity of dendritic spines: signaling messengers and actin-binding proteins
(Elsevier, 2018-09)
Activity-dependent plasticity of synaptic structure and function plays an essential role in neuronal development and in cognitive functions including learning and memory. The formation, maintenance and ...
Impaired cerebral autoregulation is associated with brain dysfunction in patients with sepsis
(Springer Nature, 2018-12-04)
Background: Sepsis-associated brain dysfunction (SABD) is associated with high morbidity and mortality. The pathophysiology of SABD is multifactorial. One hypothesis is that impaired cerebral autoregulation ...
Plataformas digitales y empleo: necesidad de monitorización y vigilancia de Salud Pública
(Ministerio de Sanidad, Consumo y Bienestar Social, 2018)
Actualmente, la relación entre las condiciones del trabajo y empleo con la salud es bien conocida, además esta relación es un importante determinante social de la salud de la población trabajadora ...
Evaluation of RETICs glaucoma diagnostic calculators in preperimetric glaucoma
(Association for Research in Vision and Ophthalmology, 2018-11)
Purpose: To evaluate two glaucoma diagnostic calculators (GDC) in a group of eyes with preperimetric glaucoma (PPG).
Methods: All eyes (n = 265) included in this study had ocular hypertension with ...
ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer
(Impact Journals, 2018-03-30)
Endometrial cancer (EC) is the sixth deadliest cancer in women. The depth of myometrial invasion is one of the most important prognostic factors, being directly associated with tumor recurrence and ...
Unliganded progesterone receptor governs estrogen receptor gene expression by regulating DNA methylation in breast cancer cells
(MDPI, 2018)
Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ...
Understanding perceived availability and importance of tobacco control interventions to inform European adoption of a UK economic model: a cross-sectional study
(BMC, 2018-02-14)
Background:
The evidence on the extent to which stakeholders in different European countries agree with availability and importance of tobacco-control interventions is limited. This study assessed and ...
Predicting patient-ventilator asynchronies with hidden markov models
(Springer Nature, 2018-12-04)
In mechanical ventilation, it is paramount to ensure the patient’s ventilatory demand is met while minimizing asynchronies. We aimed to develop a model to predict the likelihood of asynchronies occurring. ...
“EspaiJove.net”- a school-based intervention programme to promote mental health and eradicate stigma in the adolescent population: study protocol for a cluster randomised controlled trial
(Springer Nature, 2018)
Background: One half of adults who develop any mental disorder do so during adolescence. Previous literature showed that Mental Health Literacy (MHL) interventions impact mental health knowledge, reduce ...
CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy
(Nature Research, 2018-05-03)
Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some
applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to
improve ...