• Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer 

      Ricco Pacheco, Natalia; Flor, Amy; Wolfgeher, Donald; Efimova, Elena V.; Ramamurthy, Aishwarya; Appelbe, Oliver K.; Brinkman, Jacqueline; Truman, Andrew W.; Spiotto, Michael T.; Kron, Stephen J. (Molecular Oncology, 2019-06-21)
      Radioresistance is a major hurdle in the treatment of head and neck squamous cell carcinoma (HNSCC). Here, we report that concomitant treatment of HNSCCs with radiotherapy and mevalonate pathway inhibitors ...