Browsing by Author "Reguera, Ana Cristina"

Now showing items 1-4 of 4

    • Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status 

      Miralpeix Monclús, Cristina; Reguera, Ana Cristina; Fosch, Anna; Casas, Maria; Lillo, Jaume; Navarro, Gemma; Franco, Rafael; Casas, Josefina; Alexander, Stephen P.H.; Casals i Farré, Núria; Rodríguez-Rodríguez, Rosalía (British Journal of Pharmacology, 2021-01)
      Background and Purpose: The enzyme α/β‐hydrolase domain containing 6 (ABHD6), a new member of the endocannabinoid system, is a promising therapeutic target against neuronal‐related diseases. However, ...

    • Central regulation of brown fat thermogenesis in response to saturated or unsaturated long-chain fatty acids 

      Fosch Masllovet, Anna; Rodríguez García, Maria; Miralpeix , Cristina; Zagmutt, Sebastián; Larrañaga Fernandez, Maite; Reguera, Ana Cristina; Garcia-Chica, Jesus; Herrero, Laura; Serra, Dolors; Casals, Nuria; Rodriguez-Rodriguez, Rosalia (International Journal of Molecular Sciences, 2023)
      Sensing of long-chain fatty acids (LCFA) in the hypothalamus modulates energy balance, and its disruption leads to obesity. To date, the effects of saturated or unsaturated LCFA on hypothalamic-brown ...

    • Hypothalamic endocannabinoids in obesity: an old story with new challenges 

      Miralpeix Monclús, Cristina; Reguera, Ana Cristina; Fosch, Anna; Zagmutt, Sebastián; Casals i Farré, Núria; Cota, Daniela; Rodríguez-Rodríguez, Rosalía (Cellular and Molecular Life Sciences, 2021)
      The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and cellular mechanisms involved are the focus of intense research. A disrupted ...

    • Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance 

      Garcia-Chica, Jesús; Paraiso, West Kristian; Zagmutt, Sebastián; Fosch, Anna; Reguera, Ana Cristina; Alzina, Sara; Sánchez-García, Laura; Fukushima, Shigeto; Toh, Kazuko; Casals, Núria; Serra, Dolors; Herrero, Laura; Garcia Gomez, Jordi; Kataoka, Kazunori; Ariza, Xavier; Quader, Sabina; Rodriguez-Rodriguez, Rosalia (Biomaterials Science, 2023)
      Targeting brain lipid metabolism is a promising strategy to regulate the energy balance and fight metabolic diseases such as obesity. The development of stable platforms for selective delivery of drugs, ...