Browsing by Author "Launes, Cristian"
Now showing items 1-15 of 15
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Association between soluble angiotensin-converting enzyme 2 in saliva and SARS-CoV-2 infection: a cross-sectional study
Bru, Samuel; Brotons, Pedro; Jordan, Iolanda; Alsina, Laia; Henares, Desiree; Carballar, Reyes; Fernandez de Sevilla, Mariona; Barrabeig, Irene; Fumado, Victoria; Baro, Bàrbara; Martínez-Láinez, Joan Marc; Garcia-Garcia, Juan J.; Bassat, Quique; Balaguer, Albert; Clotet, Josep; Launes, Cristian; Muñoz Almagro, Carmen (Scientific Reports, 2023)This study aimed to investigate the association between saliva soluble angiotensin-converting enzyme 2 (sACE2) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and ... -
Cerebrospinal fluid neopterin as a biomarker of neuroinflammatory diseases
Molero‑Luis, Marta; Casas-Alba, Didac; Orellana, Gabriela; Ormazabal, Aida; Sierra, Cristina; Oliva, Clara; Valls, Anna; Velasco, Jesus; Launes, Cristian; Cuadras, Daniel; Pérez‑Dueñas, Belén; Jordan, Iolanda; Cambra, Francisco J.; Ortigoza‑Escobar, Juan D.; Muñoz-Almagro, Carmen; Garcia‑Cazorla, Angels; Armangué, Thais; Artuch, Rafael (Scientific Reports, 2020)The elevation of neopterin in cerebrospinal fluid (CSF) has been reported in several neuroinflammatory disorders. However, it is not expected that neopterin alone can discriminate among different ... -
Concentrations of nitrogen compounds are related to severe rhinovirus infection in infants. A time-series analysis from the reference area of a pediatric university hospital in Barcelona
Armero, Georgina; Penela Sánchez, Daniel; Belmonte, Jordina; Gómez-Barroso, Diana; Larrauri, Amparo; Henares Bonilla , Desirée; Vallejo, Violeta; Jordan, Iolanda; Muñoz-Almagro, Carmen; Brotons, Pedro; Launes, Cristian (Pediatric Pulmonology, 2022)Background: There is scarce information focused on the effect of weather conditions and air pollution on specific acute viral respiratory infections, such as rhinovirus (RV), with a wide clinical spectrum ... -
Exploring the nasopharyngeal microbiota composition in infants with whooping cough: a test-negative case-control study
Rocafort, Muntsa; Henares, Desiree; Brotons, Pedro; Barrabeig, Irene; Launes, Cristian; Merdrignac, Lore; Valenciano, Marta; Domínguez, Angela; Godoy, Pere; Muñoz-Almagro, Carmen (PLoS One, 2021)Purpose: The purpose of this study was to characterize the nasopharyngeal microbiota of infants with possible and confirmed pertussis compared to healthy controls. Methods: This prospective study included ... -
Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis
Leon, Kristoffer E.; Schubert, Ryan D.; Casas-Alba, Didac; Hawes, Isobel A.; Ramachandran, Prashanth S.; Ramesh, Akshaya; Pak, John E.; Wu, Wesley; Cheung, Carly K.; Crawford, Emily D.; Khan, Lillian M.; Launes, Cristian; Sample, Hannah A.; Zorn, Kelsey C.; Cabrerizo, María; Valero-Rello, Ana; Langelier, Charles; Muñoz-Almagro, Carmen; DeRisi, Joseph L.; Wilson, Michael R. (Neurology: Neuroimmunology & Neuroinflammation, 2020)Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ... -
Impact of COVID-19 lockdown on the nasopharyngeal microbiota of children and adults self-confined at home
Rocafort, Muntsa; Henares, Desiree; Brotons, Pedro; Launes, Cristian; de Sevilla, Mariona F; Fumado, Victoria; Barrabeig, Irene; Arias, Sara; Redin, Alba; Ponomarenko, Julia; Melé-Casas, Maria; Millat-Martinez, Pere; Claverol, Joana; Balanza, Nuria; Mira, Alex; Garcia-Garcia, Juan J.; Bassat, Quique; Jordan, Iolanda; Muñoz-Almagro, Carmen (Viruses, 2022)The increased incidence of COVID-19 cases and deaths in Spain in March 2020 led to the declaration by the Spanish government of a state of emergency imposing strict confinement measures on the population. ... -
Impact of the bacterial nasopharyngeal microbiota on the severity of genus enterovirus lower respiratory tract infection in children: a case–control study
Penela Sánchez, Daniel; Rocafort, Muntsa; Henares, Desiree; Jordan, Iolanda; Brotons, Pedro; Cabrerizo, María; Launes, Cristian; Muñoz Almagro, Carmen (Pediatric Pulmonology, 2023)Introduction: Rhinoviruses (RV) and enteroviruses (EV) are among the main causative etiologies of lower respiratory tract infection (LRTI) in children. The clinical spectrum of RV/EV infection is wide, ... -
Low transmission of SARS-CoV-2 derived from children in family clusters: an observational study of family households in the Barcelona Metropolitan Area, Spain
Mele-Casas, Maria; Launes, Cristian; F. de Sevilla, Mariona; Hernandez-Garcia, Maria; Pons-Tomas, Gemma; Bassat, Quique; Fumado, Victoria; Fortuny, Claudia; Garcia-Miquel, Aleix; Bonet-Carne, Elisenda; Prats, Clara; Ajanovic, Sara; Cubells, Marta; Claverol, Joana; Penela-Sanchez, Daniel; Jou, Cristina; Arias, Sara; Balanza, Nuria; Baro, Barbara; Millat-Martinez, Pere; Alonso, Sergio; Alvarez-Lacalle, Enric; Catala, Marti; Cuadras, Daniel; Muñoz-Almagro, Carmen; Gratacos, Eduard; Jordan, Iolanda; Garcia-Garcia, Juan Jose (PLoS ONE, 2022)Background: Family clusters offer a good opportunity to study viral transmission in a stable setting. We aimed to analyze the specific role of children in transmission of SARS-CoV-2 within households. ... -
Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016
González-Sanz, Rubén; Casas-Alba, Didac; Launes, Cristian; Muñoz-Almagro, Carmen; Ruiz-García, María Montserrat; Alonso, Mercedes; González-Abad, María José; Megías, Gregoria; Rabella, Nuria; Del Cuerpo, Margarita; Gozalo Margüello, Mónica; González-Praetorius, Alejandro; Martínez-Sapiña, Ana; Goyanes-Galán, María José; Romero, María Pilar; Calvo, Cristina; Antón, Andrés; Imaz, Manuel; Aranzamendi, Maitane; Hernández-Rodríguez, Águeda; Moreno-Docón, Antonio; Rey-Cao, Sonia; Navasués, Ana; Otero, Almudena; Cabrerizo, María (Eurosurveillance, 2019-02)Enterovirus 71 (EV-A71) is a small, non-enveloped, single-stranded RNA virus that belongs to the species Enterovirus A along with 24 other serotypes within the Enterovirus genus [1]. According to the ... -
The positive rhinovirus/enterovirus detection and SARS-CoV-2 persistence beyond the acute infection phase: an intra-household surveillance study
Brotons de Los Reyes, Pedro; Jordan, Iolanda; Bassat, Quique; Henares, Desirée; Fernandez de Sevilla, Mariona; Ajanovic, Sara; Redin, Alba; Fumado, Vicky; Baro, Bàrbara; Claverol, Joana; Varo, Rosauro; Cuadras, Daniel; Hecht, Jochen; Barrabeig, Irene; Garcia-Garcia, Juan Jose; Launes, Cristian; Muñoz-Almagro, Carmen (Viruses, 2021)We aimed to assess the duration of nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA persistence in adults self-confined at home after acute infection; and to identify the ... -
Procalcitonin-guidance reduces antibiotic exposure in children with nosocomial infection (PRORANI)
Launes, Cristian; Esteban, Elisabeth; Balaguer, Mònica; Alsina, Miquel; Cambra, Francisco-José; Jordan, Iolanda (Journal of Infection, 2016) -
Rapid increase of oral bacteria in nasopharyngeal microbiota after antibiotic treatment in children with invasive pneumococcal disease
Henares, Desirée; Rocafort, Muntsa; Brotons, Pedro; De Sevilla, Mariona F.; Mira, Alex; Launes, Cristian; Cabrera-Rubio, Raul; Muñoz-Almagro, Carmen (Frontiers in Cellular and Infection Microbiology, 2021)Introduction: Antibiotics are commonly prescribed to young children for treating bacterial infections such as invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae. Despite the obvious ... -
Rapid molecular syndromic testing for aetiological diagnosis of gastrointestinal infections and targeted antimicrobial prescription: experience from a reference paediatric hospital in Spain
Castany-Feixas, Marta; Simo, Silvia; Garcia-Garcia, Selene; Fernandez de Sevilla, Mariona; Launes, Cristian; Kalkgruber, Marlene; Gene, Amadeu; Muñoz-Almagro, Carmen; Brotons, Pedro (European Journal of Clinical Microbiology & Infectious Diseases, 2021)Aetiological diagnosis of gastrointestinal infections is challenging since a wide range of bacteria, parasites and viruses can be causal agents and derived clinical manifestations appear quite similar. ... -
Susceptibility to severe acute respiratory syndrome coronavirus 2 infection among children and adults: a seroprevalence study of family households in the Barcelona metropolitan region, Spain
Brotons, Pedro; Launes, Cristian; Buetas, Elena; Fumado, Vicky; Henares, Desirée; Fernandez de Sevilla, Mariona; Redin, Alba; Fuente-Soro, Laura; Cuadras, Daniel; Melé Casas, María; Jou, Cristina; Millat-Martínez, Pere; Jordan, Iolanda; Garcia-Garcia, Juan Jose; Bassat, Quique; Muñoz-Almagro, Carmen; Kids Corona Study Group (Clinical Infectious Diseases, 2021-06)Background: Susceptibility of children and adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and persistence of antibody response to the virus after infection resolution ... -
Validation and implementation of a direct RT-qPCR method for rapid screening of SARS-CoV-2 infection by using non-invasive saliva samples
Brotons de Los Reyes, Pedro; Perez-Argüello, Amaresh; Launes, Cristian; Torrents, Francesc; Subirats, Maria Pilar; Saucedo, Jesica; Claverol, Joana; Garcia-Garcia, Juan Jose; Rodas Font, Gil; Fumado, Vicky; Jordan, Iolanda; Gratacos, Eduard; Bassat, Quique; Muñoz-Almagro, Carmen (International Journal of Infectious Diseases, 2021)Objective: To validate and implement an optimized screening method for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA combining use of self-collected raw saliva samples, ...