Visualitzant per autor/a "Jiménez Jiménez, Javier"

Ara mostrant els elements 1-7 de 7

    • Caracterización de complejos CDK-Ciclina atípicos humanos 

      Quandt Herrera, Eva (Data de defensa: 2018-03-15)
      La desregulación en los mecanismos de control del ciclo celular es un evento indiscutiblemente asociado a la aparición de diversas patologías, entre las que destacan los procesos tumorales. Como principales ...

    • CDK-mediated phosphorylation of Yku80 and its role in DNA repair 

      Carballar Ruiz, María de los Reyes (Data de defensa: 2021-03-11)
      DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining ...

    • Covid-19, an opportunity to compare in-person and online teaching 

      Bru, Samuel; Ribeiro, Mariana PC; Quandt, Eva; Clotet, Josep; Jiménez Jiménez, Javier (Revista Española de Educación Médica, 2021)
      For years it has been discussed the dichotomy between traditional in-person teaching versus online instruction. The lockdown, consequence of the Covid-19 pandemic, gave us an opportunity to gain evidence ...

    • Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex 

      Hernández Ortega, Sara; Sánchez Botet, Abril; Quandt Herrera, Eva; Masip, Núria; Gasa Colom, Laura; Verde, Gaetano; Jiménez Jiménez, Javier; Levin, Rebecca; Rugatanira, Florentine U.; Burlingame, Alma L.; Wolfgeher, Donald; P.C. Ribeiro, Mariana; Kron, Stephen J.; M. Shokat, Kevan; Clotet Erra, Josep (2019)
      CDK16 (also known as PCTAIRE1 or PCTK1) is an atypical member of the cyclin-dependent kinase (CDK) family that forms an active complex with cyclin Y (CCNY). Although both proteins have been recently ...

    • Regulación del ciclo celular por ploidía en Saccharomyces cerevisiae 

      Martínez Láinez, Joan Marc (Data de defensa: 2018-02-02)
      Una de les característiques cel·lulars amb més impacte sobre la seva fisiologia cel·lular és la mida, regulada per multitud de factors extrínsecs i intrínsecs, i una característica de vital rellevància ...

    • A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer 

      Gasa Colom, Laura; Sánchez Botet, Abril; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Carrasco García, Miguel Ángel; Simonetti, Sara; Kron, Stephen J.; P.C. Ribeiro, Mariana; Nadal, E; Villanueva, Alberto; Clotet Erra, Josep (2017-08-31)
      As lung cancer has increased to the most common cause of cancer death worldwide, prognostic biomarkers and efective targeted treatments remain lacking despite advances based on patients’ stratifcation. ...

    • The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration 

      Sánchez Botet, Abril; Gasa Colom, Laura; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Mezquita Mas, Pau; Carrasco García, Miguel Ángel; Kron, Stephen J.; Vidal, August; Villanueva, Alberto; P.C. Ribeiro, Mariana; Clotet Erra, Josep (2018-08-07)
      Colorectal cancer (CRC) is one of the most common cancers worldwide, with 8–10% of these tumours presenting a BRAF (V600E) mutation. Cyclins are known oncogenes deregulated in many cancers, but the role ...